Rome2Rio

Indianapolis to Chicago Bus Station buses

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Trip Overview

The average bus between Indianapolis and Chicago Bus Station takes 3h 59m and the fastest bus takes 3h 20m. The bus service runs several times per day from Indianapolis to Chicago Bus Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 59m
Duration
183 mi
Distance
$40
Average price
Every 2 hours
Frequency

Indianapolis to Chicago Bus Station bus times

Buses run every 2 hours between Indianapolis and Chicago Bus Station. The earliest departure is at 3:15 AM at night, and the last departure from Indianapolis is at 9:50 PM which arrives into Chicago Bus Station at 12:10 AM. All services run direct with no transfers required, and take on average 3h 59m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

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    bus bus 4h 45m • Direct
  •  → 

    bus bus 3h 40m • Direct
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    bus bus 3h 40m • Direct
  •  → 

    bus bus 3h 35m • Direct
  • Show more

Departing Wednesday, November 11, 2026

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    bus bus 4h 5m • Direct
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    bus bus 5h • Direct
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    bus bus 4h 25m • Direct
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    bus bus 3h 30m • Direct
  • Show more

Departing Thursday, November 12, 2026

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    bus bus 3h 55m • Direct
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    bus bus 4h 5m • Direct
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    bus bus 5h • Direct
  •  → 

    bus bus 4h 25m • Direct
  • Show more

Departing Friday, November 13, 2026

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    bus bus 3h 55m • Direct
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    bus bus 4h 5m • Direct
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    bus bus 5h • Direct
  •  → 

    bus bus 4h 25m • Direct
  • Show more

Departing Saturday, November 14, 2026

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    bus bus 3h 55m • Direct
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    bus bus 4h 5m • Direct
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    bus bus 5h • Direct
  •  → 

    bus bus 4h 25m • Direct
  • Show more

Departing Sunday, November 15, 2026

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    bus bus 3h 55m • Direct
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    bus bus 4h 5m • Direct
  •  → 

    bus bus 5h • Direct
  •  → 

    bus bus 4h 25m • Direct
  • Show more

Departing Monday, November 16, 2026

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    bus bus 3h 55m • Direct
  •  → 

    bus bus 4h 5m • Direct
  •  → 

    bus bus 5h • Direct
  •  → 

    bus bus 4h 25m • Direct
  • Show more

Frequently asked questions

Want to know about travelling from Indianapolis to Chicago Bus Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Indianapolis to Chicago Bus Station.ExpandLaunch map view
  • Distance: 183.4 mi
  • Duration: 3h 59m

What companies run services between Indianapolis, IN, USA and Chicago Bus Station, IL, USA?

Flixbus USA operates a bus from Indianapolis to Chicago Bus Station every 4 hours. Tickets cost $29–45 and the journey takes 3h 40m. Greyhound USA also services this route 5 times a day.

Operators