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Indianapolis to Irvine buses

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Trip Overview

The average bus between Indianapolis and Irvine takes 2d 3h and the fastest bus takes 2d 1h. The bus runs, on average, 5 times per week from Indianapolis to Irvine. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 3h
Duration
2,181 mi
Distance
$408
Average price
5 times a week
Frequency

Indianapolis to Irvine bus times

Buses run 5 times a week between Indianapolis and Irvine. The earliest departure is at 7:35 PM in the evening, and the last departure from Indianapolis is at 7:35 PM which arrives into Irvine at 6:19 PM. All services require a transfer at St Louis Bus Station and take an average of 2d 3h. The schedules shown below are for the next available departures.

Departing Friday, October 9, 2026

  •  → 

    Arrives +3 days

    Greyhound USAGreyhound USAGreyhound USAOCTA2d 12h • 3 changes

Departing Saturday, October 10, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USAOCTA2d 1h • 3 changes

Departing Sunday, October 11, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USAOCTA2d 1h • 3 changes

Departing Monday, October 12, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USAOCTA2d 1h • 3 changes

Departing Tuesday, October 13, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USAOCTA2d 1h • 3 changes

Frequently asked questions

Want to know about travelling from Indianapolis to Irvine? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Indianapolis to Irvine.ExpandLaunch map view
  • Distance: 2,181.1 mi
  • Duration: 2d 3h

What companies run services between Indianapolis, IN, USA and Irvine, CA, USA?

You can take a bus from Indianapolis Union Station to Main-Harvard via St Louis Bus Station, Montclair Transcenter, Anaheim Regional Transportation Intermodal Center, and Artic - Dock 4 in around 2d.

Operators