The average bus between Indianapolis and University of Chicago takes 6h 55m and the fastest bus takes 3h 29m. The bus service runs several times per day from Indianapolis to University of Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Indianapolis and University of Chicago. The earliest departure is at 3:15 AM at night, and the last departure from Indianapolis is at 9:55 PM which arrives into University of Chicago at 12:24 AM. All services require a transfer at Chicago and take an average of 6h 55m. The schedules shown below are for the next available departures.
Arrives next day

16h 12m • 1 change
Arrives next day

2h 58m • 1 change

3h 5m • 1 change

5h 49m • 1 change
Arrives next day

2h 29m • 1 change

3h 5m • 1 change

5h 49m • 1 change
Arrives next day

2h 29m • 1 change
Want to know about travelling from Indianapolis to University of Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Indianapolis to University of Chicago. However, there are services departing from Indianapolis station and arriving at University of Chicago station via Chicago. The journey, including transfers, takes approximately 6h 55m.
Indianapolis to University of Chicago bus services, operated by Flixbus USA, depart from Indianapolis station.
Indianapolis to University of Chicago bus services, operated by Flixbus USA, arrive at Chicago station.
The distance between Indianapolis and University of Chicago is 255.4 km. The road distance is 294 km.
Flixbus USA operates a bus from Indianapolis to Chicago 5 times a day. Tickets cost $28–50 and the journey takes 3h 25m.