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Iowa City to Chicago Union Station buses

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Trip Overview

The average bus between Iowa City and Chicago Union Station takes 5h 12m and the fastest bus takes 4h 40m. The bus service runs several times per day from Iowa City to Chicago Union Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 12m
Duration
235 mi
Distance
$50
Average price
Twice daily
Frequency

Iowa City to Chicago Union Station bus times

Buses run twice daily between Iowa City and Chicago Union Station. The earliest departure is at 7:50 AM in the morning, and the last departure from Iowa City is at 11:45 AM which arrives into Chicago Union Station at 4:25 PM. All services run direct with no transfers required, and take on average 5h 12m. The schedules shown below are for the next available departures.

Departing Saturday, November 7, 2026

  •  → 

    bus bus 4h 40m • Direct

Departing Sunday, November 8, 2026

  •  → 

    bus bus 5h 45m • Direct
  •  → 

    bus bus 4h 40m • Direct

Departing Monday, November 9, 2026

  •  → 

    bus bus 5h 45m • Direct
  •  → 

    bus bus 4h 40m • Direct

Departing Tuesday, November 10, 2026

  •  → 

    bus bus 5h 45m • Direct
  •  → 

    bus bus 4h 40m • Direct

Departing Wednesday, November 11, 2026

  •  → 

    bus bus 5h 45m • Direct
  •  → 

    bus bus 4h 40m • Direct

Departing Thursday, November 12, 2026

  •  → 

    bus bus 5h 45m • Direct
  •  → 

    bus bus 4h 40m • Direct

Departing Friday, November 13, 2026

  •  → 

    bus bus 5h 45m • Direct
  •  → 

    bus bus 4h 40m • Direct

Frequently asked questions

Want to know about travelling from Iowa City to Chicago Union Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Iowa City to Chicago Union Station.ExpandLaunch map view
  • Distance: 234.7 mi
  • Duration: 5h 12m

What companies run services between Iowa City, IA, USA and Chicago Union Station, IL, USA?

Greyhound USA operates a bus from Iowa City to Chicago Bus Station 4 times a day. Tickets cost $40–65 and the journey takes 5h 45m.

Operators