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Iowa City to Indianapolis buses

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Trip Overview

The average bus between Iowa City and Indianapolis takes 13h 5m and the fastest bus takes 10h 30m. The bus runs, on average, 6 times per week from Iowa City to Indianapolis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

13h 5m
Duration
406 mi
Distance
$82
Average price
6 times a week
Frequency

Iowa City to Indianapolis bus times

Buses run 6 times a week between Iowa City and Indianapolis. The earliest departure is at 10:40 AM in the morning, and the last departure from Iowa City is at 11:40 AM which arrives into Indianapolis at 11:10 PM. All services require a transfer, and take on average 13h 5m. The schedules shown below are for the next available departures.

Departing Saturday, October 31, 2026

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    Greyhound USAFlixbus USA10h 30m • 1 change

Departing Sunday, November 1, 2026

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    Greyhound USAFlixbus USA11h 30m • 1 change

Departing Monday, November 2, 2026

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    Greyhound USAFlixbus USA10h 30m • 1 change

Departing Tuesday, November 3, 2026

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    Arrives next day

    Greyhound USAFlixbus USA24h 5m • 1 change

Departing Wednesday, November 4, 2026

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    Arrives next day

    Greyhound USAFlixbus USA11h 25m • 1 change

Departing Thursday, November 5, 2026

  •  → 

    Greyhound USAFlixbus USA10h 30m • 1 change

Frequently asked questions

Want to know about travelling from Iowa City to Indianapolis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Iowa City to Indianapolis.ExpandLaunch map view
  • Distance: 405.5 mi
  • Duration: 13h 5m

What companies run services between Iowa City, IA, USA and Indianapolis, IN, USA?

You can take a bus from Iowa City to Indianapolis via Chicago Bus Station in around 9h 30m.

Operators