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Iowa City to Jeffersonville buses

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Trip Overview

The average bus between Iowa City and Jeffersonville takes 26h 13m and the fastest bus takes 18h 38m. The bus runs, on average, 3 times per week from Iowa City to Jeffersonville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

26h 13m
Duration
527 mi
Distance
$104
Average price
3 times a week
Frequency

Iowa City to Jeffersonville bus times

Buses run 3 times a week between Iowa City and Jeffersonville. The earliest departure is at 11:40 AM in the morning, and the last departure from Iowa City is at 11:40 AM which arrives into Jeffersonville at 7:18 AM. All services require a transfer at Chicago Bus Station and take an average of 26h 13m. The schedules shown below are for the next available departures.

Departing Thursday, October 22, 2026

  •  → 

    Arrives +2 days

    Greyhound USAAmtrak ThruwayTransit Authority of River City41h 23m • 2 changes

Departing Friday, October 23, 2026

  •  → 

    Arrives next day

    Greyhound USAAmtrak ThruwayTransit Authority of River City18h 38m • 2 changes

Departing Saturday, October 24, 2026

  •  → 

    Arrives next day

    Greyhound USAAmtrak ThruwayTransit Authority of River City18h 38m • 2 changes

Frequently asked questions

Want to know about travelling from Iowa City to Jeffersonville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Iowa City to Jeffersonville.ExpandLaunch map view
  • Distance: 526.6 mi
  • Duration: 26h 13m

What companies run services between Iowa City, IA, USA and Jeffersonville, IN, USA?

You can take a bus from Iowa City to Court @ Spring via Chicago Bus Station, Chicago Union Station, Louisville, KY, and Liberty @ Roy Wilkins in around 13h 32m.

Operators