The average bus between Iowa City and St. Louis takes 12h 50m and the fastest bus takes 11h 40m. The bus runs, on average, 6 times per week from Iowa City to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 6 times a week between Iowa City and St. Louis. The earliest departure is at 11:40 AM in the morning, and the last departure from Iowa City is at 11:40 AM which arrives into St. Louis at 11:20 PM. All services require a transfer, and take on average 12h 50m. The schedules shown below are for the next available departures.
Want to know about travelling from Iowa City to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Iowa City to St. Louis. However, there are services departing from Iowa City station and arriving at St. Louis station via Chicago Bus Station station. The journey, including transfers, takes approximately 12h 50m.
Iowa City to St. Louis bus services, operated by Greyhound USA, depart from Iowa City station.
Iowa City to St. Louis bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Book your Iowa City to St. Louis bus tickets online with Greyhound USA and Flixbus USA.
The distance between Iowa City and St. Louis is 355.8 km. The road distance is 870 km.
You can take a bus from Iowa City to St Louis Bus Station via Chicago Bus Station in around 11h 40m.
