The average bus between Ioánnina and Sérres takes 5h 29m and the fastest bus takes 5h. The bus service runs several times per day from Ioánnina to Sérres. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Ioánnina and Sérres. The earliest departure is at 8:00 AM in the morning, and the last departure from Ioánnina is at 6:15 PM which arrives into Sérres at 11:15 PM. All services require a transfer, and take on average 5h 29m. The schedules shown below are for the next available departures.

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5h • 1 changeWant to know about travelling from Ioánnina to Sérres? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Ioánnina to Sérres. However, there are services departing from Ioannina station and arriving at Serres station via Thessaloniki Macedonia KTEL Bus Station. The journey, including transfers, takes approximately 5h 29m.
Ioánnina to Sérres bus services, operated by KTEL Ioanninon, depart from Ioannina station.
Ioánnina to Sérres bus services, operated by KTEL Serron, arrive at Serres station.
The distance between Ioánnina and Sérres is 277.6 km. The road distance is 339 km.
You can take a bus from Ioannina to Serres via Thessaloniki Macedonia KTEL Bus Station in around 5h 30m.