The average bus between Irvine and Kearny Mesa takes 4h 27m and the fastest bus takes 3h 23m. The bus service runs several times per day from Irvine to Kearny Mesa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Irvine and Kearny Mesa. The earliest departure is at 8:46 AM in the morning, and the last departure from Irvine is at 10:26 PM which arrives into Kearny Mesa at 5:46 AM. All services require a transfer at Santa Ana Bus Stop and take an average of 4h 27m. The schedules shown below are for the next available departures.


3h 35m • 2 changes
Arrives next day


3h 39m • 2 changes


3h 35m • 2 changes


3h 23m • 2 changes


4h • 2 changes


3h 39m • 2 changes


3h 35m • 2 changes


3h 39m • 2 changes


3h 35m • 2 changes
Want to know about travelling from Irvine to Kearny Mesa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Irvine to Kearny Mesa. However, there are services departing from Irvine station and arriving at Kearny Mesa station via The Depot At Santa Ana Dock 3. The journey, including transfers, takes approximately 4h 27m.
Irvine to Kearny Mesa bus services, operated by OCTA, depart from University-Ent 3773 Mariposa Villa station.
Irvine to Kearny Mesa bus services, operated by OCTA, arrive at San Diego Greyhound Bus Stop station.
The distance between Irvine and Kearny Mesa is 112.9 km. The road distance is 169 km.
You can take a bus from University-Ent 3773 Mariposa Villa to Clairemont Mesa Bl & 8303 via Santa Ana Bus Stop, San Diego Greyhound Bus Stop, and Old Town Transit Center in around 4h 18m.