The average bus between Irvine and La Jolla takes 5h 16m and the fastest bus takes 3h 46m. The bus service runs several times per day from Irvine to La Jolla. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Irvine and La Jolla. The earliest departure is at 8:46 AM in the morning, and the last departure from Irvine is at 9:26 PM which arrives into La Jolla at 6:03 AM. All services require a transfer at Santa Ana Bus Stop and take an average of 5h 16m. The schedules shown below are for the next available departures.


3h 50m • 2 changes

3h 46m • 2 changesArrives next day


8h 37m • 2 changes

3h 50m • 2 changes

3h 46m • 2 changesArrives next day


8h 50m • 2 changes

3h 46m • 2 changes

3h 52m • 2 changesArrives next day


9h 18m • 2 changes

3h 50m • 2 changes

3h 46m • 2 changesArrives next day


8h 37m • 2 changesWant to know about travelling from Irvine to La Jolla? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Irvine to La Jolla. However, there are services departing from Irvine station and arriving at La Jolla station via The Depot At Santa Ana Dock 3. The journey, including transfers, takes approximately 5h 16m.
Irvine to La Jolla bus services, operated by OCTA, depart from University-Ent 3773 Mariposa Villa station.
Irvine to La Jolla bus services, operated by OCTA, arrive at Silverado St & Herschel Av station.
Book your Irvine to La Jolla bus tickets online with OCTA, Greyhound USA and 2 other operators.
The distance between Irvine and La Jolla is 104.7 km. The road distance is 172 km.
You can take a bus from University-Ent 3773 Mariposa Villa to Silverado St & Herschel Av via Santa Ana Bus Stop, San Diego Greyhound Bus Stop, and Old Town Transit Center in around 4h 17m.