Rome2Rio

Irvine to La Jolla buses

Find Transport to La Jolla

View schedule

Trip Overview

The average bus between Irvine and La Jolla takes 5h 41m and the fastest bus takes 3h 44m. The bus service runs several times per day from Irvine to La Jolla. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 41m
Duration
112 mi
Distance
$24
Average price
4 times a day
Frequency

Line 53 bus, bus, line 30 bus

best
  1. Take the bus from Main-Harvard to Artic - Dock 4bus bus 53
  2. Take the bus from Anaheim Regional Transportation Intermodal Center to San Diego Greyhound Bus Stopbus bus
  3. Take the bus from Old Town Transit Center to Silverado St & Herschel Avbus bus 30
4h 28m
$17–30

Irvine to La Jolla bus times

Buses run 4 times a day between Irvine and La Jolla. The earliest departure is at 8:31 AM in the morning, and the last departure from Irvine is at 11:45 PM which arrives into La Jolla at 12:24 PM. All services require a transfer at Artic - Dock 4 and take an average of 5h 41m. The schedules shown below are for the next available departures.

Departing Friday, October 16, 2026

  •  → 

    OCTAGreyhound USASan Diego Metro Transit3h 58m • 2 changes

  •  → 

    Arrives next day

    OCTAGreyhound USASan Diego Metro Transit9h 34m • 2 changes

Departing Saturday, October 17, 2026

  •  → 

    OCTAFlixbus USASan Diego Metro Transit3h 44m • 2 changes

  •  → 

    OCTAFlixbus USASan Diego Metro Transit4h 16m • 2 changes

  •  → 

    OCTAGreyhound USASan Diego Metro Transit4h 15m • 2 changes

  •  → 

    Arrives next day

    OCTAGreyhound USASan Diego Metro Transit9h 51m • 2 changes
  • Show more

Departing Monday, October 19, 2026

  •  → 

    OCTAFlixbus USASan Diego Metro Transit3h 50m • 2 changes

  •  → 

    OCTAFlixbus USASan Diego Metro Transit4h 21m • 2 changes

  •  → 

    OCTAGreyhound USASan Diego Metro Transit3h 58m • 2 changes

  •  → 

    Arrives next day

    OCTAGreyhound USASan Diego Metro Transit9h 21m • 2 changes

Departing Tuesday, October 20, 2026

  •  → 

    OCTAFlixbus USASan Diego Metro Transit3h 50m • 2 changes

  •  → 

    OCTAFlixbus USASan Diego Metro Transit4h 21m • 2 changes

  •  → 

    OCTAGreyhound USASan Diego Metro Transit3h 58m • 2 changes

  •  → 

    Arrives next day

    OCTAGreyhound USASan Diego Metro Transit9h 21m • 2 changes

Departing Wednesday, October 21, 2026

  •  → 

    OCTAFlixbus USASan Diego Metro Transit3h 50m • 2 changes

  •  → 

    OCTAGreyhound USASan Diego Metro Transit3h 58m • 2 changes

  •  → 

    Arrives next day

    OCTAGreyhound USASan Diego Metro Transit9h 21m • 2 changes

Departing Thursday, October 22, 2026

  •  → 

    OCTAFlixbus USASan Diego Metro Transit3h 50m • 2 changes

  •  → 

    OCTAFlixbus USASan Diego Metro Transit4h 21m • 2 changes

Frequently asked questions

Want to know about travelling from Irvine to La Jolla? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Irvine to La Jolla.ExpandLaunch map view
  • Distance: 112.3 mi
  • Duration: 5h 41m

What companies run services between Irvine, CA, USA and La Jolla, San Diego County, CA, USA?

You can take a bus from Main-Harvard to Silverado St & Herschel Av via Artic - Dock 4, Anaheim Regional Transportation Intermodal Center, San Diego Greyhound Bus Stop, and Old Town Transit Center in around 4h 28m.

Operators