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Irvine to La Jolla buses

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Trip Overview

The average bus between Irvine and La Jolla takes 5h 45m and the fastest bus takes 3h 44m. The bus service runs several times per day from Irvine to La Jolla. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 45m
Duration
112 mi
Distance
$26
Average price
4 times a day
Frequency

Irvine to La Jolla bus times

Buses run 4 times a day between Irvine and La Jolla. The earliest departure is at 8:31 AM in the morning, and the last departure from Irvine is at 11:45 PM which arrives into La Jolla at 12:54 PM. All services require a transfer at Artic - Dock 4 and take an average of 5h 45m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

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    Arrives next day

    OCTAGreyhound USASan Diego Metro Transit9h 21m • 2 changes

Departing Wednesday, November 11, 2026

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    OCTAFlixbus USASan Diego Metro Transit4h 5m • 2 changes
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    OCTAGreyhound USASan Diego Metro Transit3h 58m • 2 changes
  •  → 

    Arrives next day

    OCTAGreyhound USASan Diego Metro Transit9h 21m • 2 changes

Departing Thursday, November 12, 2026

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    OCTAFlixbus USASan Diego Metro Transit4h 5m • 2 changes
  •  → 

    OCTAFlixbus USASan Diego Metro Transit4h 21m • 2 changes
  •  → 

    OCTAGreyhound USASan Diego Metro Transit3h 58m • 2 changes
  •  → 

    Arrives next day

    OCTAGreyhound USASan Diego Metro Transit9h 21m • 2 changes

Departing Friday, November 13, 2026

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    OCTAFlixbus USASan Diego Metro Transit4h 5m • 2 changes
  •  → 

    OCTAFlixbus USASan Diego Metro Transit4h 21m • 2 changes
  •  → 

    OCTAGreyhound USASan Diego Metro Transit3h 58m • 2 changes
  •  → 

    Arrives next day

    OCTAGreyhound USASan Diego Metro Transit9h 34m • 2 changes

Departing Saturday, November 14, 2026

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    OCTAFlixbus USASan Diego Metro Transit3h 44m • 2 changes
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    OCTAFlixbus USASan Diego Metro Transit4h 16m • 2 changes
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    OCTAGreyhound USASan Diego Metro Transit4h 15m • 2 changes
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    Arrives next day

    OCTAGreyhound USASan Diego Metro Transit9h 51m • 2 changes
  • Show more

Departing Monday, November 16, 2026

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    OCTAFlixbus USASan Diego Metro Transit4h 5m • 2 changes

Frequently asked questions

Want to know about travelling from Irvine to La Jolla? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Irvine to La Jolla.ExpandLaunch map view
  • Distance: 112.3 mi
  • Duration: 5h 45m

What companies run services between Irvine, CA, USA and La Jolla, San Diego County, CA, USA?

You can take a bus from Main-Harvard to Silverado St & Herschel Av via Artic - Dock 4, Anaheim Regional Transportation Intermodal Center, San Diego Greyhound Bus Stop, and Old Town Transit Center in around 4h 28m.

Operators