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Irvine to La Mesa buses

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Trip Overview

The average bus between Irvine and La Mesa takes 6h 12m and the fastest bus takes 4h 9m. The bus service runs several times per day from Irvine to La Mesa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

6h 12m
Duration
111 mi
Distance
$38
Average price
3 times a day
Frequency

Line 59 bus, bus

best
  1. Take the bus from University-Ent 3773 Mariposa Villa to The Depot At Santa Ana Dock 3bus bus 59
  2. Take the bus from Santa Ana to San Diegobus bus Los Angeles
4h 8m
$22–44

Irvine to La Mesa bus times

Buses run 3 times a day between Irvine and La Mesa. The earliest departure is at 8:46 AM in the morning, and the last departure from Irvine is at 10:26 PM which arrives into La Mesa at 6:51 AM. All services require a transfer at The Depot At Santa Ana Dock 3 and take an average of 6h 12m. The schedules shown below are for the next available departures.

Frequently asked questions

Want to know about travelling from Irvine to La Mesa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Irvine to La Mesa.ExpandLaunch map view
  • Distance: 110.6 mi
  • Duration: 6h 12m

What companies run services between Irvine, CA, USA and La Mesa, CA, USA?

You can take a bus from University-Ent 3773 Mariposa Villa to La Mesa Blvd Station via The Depot At Santa Ana Dock 3, Santa Ana, San Diego, and 12th & Imperial Station in around 4h 8m.

Operators