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Irvine to Otay Mesa buses

Find Transport to Otay Mesa

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Trip Overview

The average bus between Irvine and Otay Mesa takes 5h 2m and the fastest bus takes 4h 21m. The bus service runs several times per day from Irvine to Otay Mesa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 2m
Duration
127 mi
Distance
$33
Average price
5 times a day
Frequency

Line 59 bus, bus

best
  1. Take the bus from University-Ent 3773 Mariposa Villa to The Depot At Santa Ana Dock 3bus bus 59
  2. Take the bus from Santa Ana to San Ysidrobus bus Lxus 3105 / ...
4h 22m
$23–47

Irvine to Otay Mesa bus times

Buses run 5 times a day between Irvine and Otay Mesa. The earliest departure is at 5:27 AM in the morning, and the last departure from Irvine is at 10:26 PM which arrives into Otay Mesa at 5:03 AM. All services require a transfer at The Depot At Santa Ana Dock 3 and take an average of 5h 2m. The schedules shown below are for the next available departures.

Frequently asked questions

Want to know about travelling from Irvine to Otay Mesa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Irvine to Otay Mesa.ExpandLaunch map view
  • Distance: 127.3 mi
  • Duration: 5h 2m

What companies run services between Irvine, CA, USA and Otay Mesa, CA, USA?

You can take a bus from University-Ent 3773 Mariposa Villa to Otay Mesa Rd & Cactus Rd via The Depot At Santa Ana Dock 3, Santa Ana, San Ysidro, San Ysidro Transit Center, and Iris Avenue Transit Center in around 4h 22m.

Operators