The average bus between Irvine and Rancho Santa Margarita takes 3h 45m and the fastest bus takes 2h 30m. There is a bus service every few hours from Irvine to Rancho Santa Margarita. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Irvine and Rancho Santa Margarita. The earliest departure is at 4:27 AM at night, and the last departure from Irvine is at 11:48 PM which arrives into Rancho Santa Margarita at 6:24 AM. All services require a transfer at Artic - Dock 5 and take an average of 3h 45m. The schedules shown below are for the next available departures.



2h 30m • 3 changes



2h 48m • 3 changes



2h 58m • 3 changes



3h 21m • 3 changes



2h 30m • 3 changes



2h 48m • 3 changes



2h 58m • 3 changes



3h 21m • 3 changes



3h 17m • 3 changes



3h 27m • 3 changes



3h 35m • 3 changes



3h 40m • 3 changes
Want to know about travelling from Irvine to Rancho Santa Margarita? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Irvine to Rancho Santa Margarita. However, there are services departing from Irvine station and arriving at Rancho Santa Margarita station via Artic - Dock 4. The journey, including transfers, takes approximately 3h 45m.
Irvine to Rancho Santa Margarita bus services, operated by OCTA, depart from Main-Harvard station.
Irvine to Rancho Santa Margarita bus services, operated by OCTA, arrive at Santa Margarita-Avd Empresa station.
The distance between Irvine and Rancho Santa Margarita is 20.6 km. The road distance is 71 km.
You can take a bus from Main-Harvard to Santa Margarita-Avd Empresa via Artic - Dock 5, Katella-Harbor, and Laguna Hills Trans Ctr Dock 4 in around 3h 41m.