Rome2Rio

Irvine to Salem buses

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Trip Overview

The average bus between Irvine and Salem takes 35h 45m and the fastest bus takes 30h 39m. The bus runs, on average, 6 times per week from Irvine to Salem. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

35h 45m
Duration
1,081 mi
Distance
$226
Average price
6 times a week
Frequency

Irvine to Salem bus times

Buses run 6 times a week between Irvine and Salem. The earliest departure is at 6:33 AM in the morning, and the last departure from Irvine is at 8:58 PM which arrives into Salem at 8:20 PM. All services require a transfer at Santa Ana Bus Stop and take an average of 35h 45m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    OCTAGreyhound USAGreyhound USAFlixbus USA37h 29m • 3 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    OCTAGreyhound USAGreyhound USAFlixbus USA30h 39m • 3 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    OCTAGreyhound USAGreyhound USAFlixbus USA37h 29m • 3 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    OCTAGreyhound USAGreyhound USAFlixbus USA30h 57m • 3 changes
  •  → 

    Arrives +2 days

    OCTAGreyhound USAGreyhound USAFlixbus USA47h 22m • 3 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    OCTAGreyhound USAGreyhound USAFlixbus USA30h 39m • 3 changes

Frequently asked questions

Want to know about travelling from Irvine to Salem? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Irvine to Salem.ExpandLaunch map view
  • Distance: 1,080.6 mi
  • Duration: 35h 45m

What companies run services between Irvine, CA, USA and Salem, OR, USA?

You can take a bus from University-Ent 3773 Mariposa Villa to Salem via Santa Ana Bus Stop, Sacramento Bus Station, and Portland Curbside Bus Stop in around 29h 19m.

Operators