The average bus between Irvine and San Diego takes 3h 32m and the fastest bus takes 2h 56m. There is at least one bus per day from Irvine to San Diego. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Irvine and San Diego. The earliest departure is at 7:06 PM in the evening, and the last departure from Irvine is at 10:26 PM which arrives into San Diego at 2:15 AM. All services require a transfer, and take on average 3h 32m. The schedules shown below are for the next available departures.
Want to know about travelling from Irvine to San Diego? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Irvine to San Diego. However, there are services departing from Irvine station and arriving at San Diego station via The Depot At Santa Ana Dock 3. The journey, including transfers, takes approximately 3h 32m.
Irvine to San Diego bus services, operated by OCTA, depart from University-Ent 3773 Mariposa Villa station.
Irvine to San Diego bus services, operated by OCTA, arrive at San Diego station.
Book your Irvine to San Diego bus tickets online with OCTA, Flixbus USA and Jefferson Lines.
The distance between Irvine and San Diego is 122.6 km. The road distance is 161 km.
You can take a bus from University-Ent 3773 Mariposa Villa to San Diego via Santa Ana Bus Stop in around 3h 29m.