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Irvine to San Francisco buses

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Trip Overview

The average bus between Irvine and San Francisco takes 14h 20m and the fastest bus takes 9h 44m. The bus runs, on average, 5 times per week from Irvine to San Francisco. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

14h 20m
Duration
432 mi
Distance
$82
Average price
5 times a week
Frequency

Irvine to San Francisco bus times

Buses run 5 times a week between Irvine and San Francisco. The earliest departure is at 10:45 PM at night, and the last departure from Irvine is at 11:45 PM which arrives into San Francisco at 8:30 AM. All services require a transfer at Artic - Dock 4 and take an average of 14h 20m. The schedules shown below are for the next available departures.

Departing Thursday, November 5, 2026

  •  → 

    Arrives next day

    OCTAFlixbus USA9h 44m • 1 change

Departing Friday, November 6, 2026

  •  → 

    Arrives next day

    OCTAFlixbus USA9h 44m • 1 change

Departing Saturday, November 7, 2026

  •  → 

    Arrives next day

    OCTAFlixbus USA9h 45m • 1 change
  •  → 

    Arrives +2 days

    OCTAFlixbus USA32h 45m • 1 change

Frequently asked questions

Want to know about travelling from Irvine to San Francisco? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Irvine to San Francisco.ExpandLaunch map view
  • Distance: 432.5 mi
  • Duration: 14h 20m

What companies run services between Irvine, CA, USA and San Francisco, CA, USA?

Flixbus USA operates a bus from Anaheim Regional Transportation Intermodal Center to San Francisco twice daily. Tickets cost $65–100 and the journey takes 8h 15m.

Operators