The average bus between Irvine and UC San Diego Medical Center takes 4h 53m and the fastest bus takes 3h 10m. The bus service runs several times per day from Irvine to UC San Diego Medical Center. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Irvine and UC San Diego Medical Center. The earliest departure is at 8:46 AM in the morning, and the last departure from Irvine is at 9:26 PM which arrives into UC San Diego Medical Center at 6:01 AM. All services require a transfer at Santa Ana Bus Stop and take an average of 4h 53m. The schedules shown below are for the next available departures.


3h 10m • 2 changes


3h 27m • 2 changes
Arrives next day


9h 33m • 2 changes


3h 18m • 2 changes


3h 13m • 2 changes
Arrives next day


8h 35m • 2 changes


3h 18m • 2 changes


3h 13m • 2 changes
Arrives next day


8h 35m • 2 changes


3h 18m • 2 changes


3h 13m • 2 changes
Arrives next day


8h 35m • 2 changes
Want to know about travelling from Irvine to UC San Diego Medical Center? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Irvine to UC San Diego Medical Center. However, there are services departing from Irvine station and arriving at UC San Diego Medical Center station via The Depot At Santa Ana Dock 3. The journey, including transfers, takes approximately 4h 53m.
Irvine to UC San Diego Medical Center bus services, operated by OCTA, depart from University-Ent 3773 Mariposa Villa station.
Irvine to UC San Diego Medical Center bus services, operated by OCTA, arrive at San Diego Greyhound Bus Stop station.
The distance between Irvine and UC San Diego Medical Center is 118.7 km. The road distance is 160 km.
You can take a bus from University-Ent 3773 Mariposa Villa to UC San Diego Medical Center via Santa Ana Bus Stop, San Diego Greyhound Bus Stop, Old Town Transit Center, and Washington St & Albatross St in around 4h 6m.