The bus between Isernia and Brindisi takes 16h 49m. The bus runs, on average, 6 times per week from Isernia to Brindisi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 6 times a week between Isernia and Brindisi. The earliest departure is at 5:16 PM in the evening, and the last departure from Isernia is at 5:16 PM which arrives into Brindisi at 10:05 AM. All services require a transfer, and take on average 16h 49m. The schedules shown below are for the next available departures.
Want to know about travelling from Isernia to Brindisi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Isernia to Brindisi. However, there are services departing from Isernia station and arriving at Brindisi station via Foggia. The journey, including transfers, takes approximately 16h 49m.
Isernia to Brindisi bus services, operated by FlixBus, depart from Isernia station.
Isernia to Brindisi bus services, operated by FlixBus, arrive at Brindisi station.
Book your Isernia to Brindisi bus tickets online with FlixBus.
The distance between Isernia and Brindisi is 328.1 km. The road distance is 423 km.
You can take a bus from Isernia to Brindisi via Foggia in around 7h 24m.