The bus between Isernia and Siena takes 5h 35m. There is at least one bus per day from Isernia to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Isernia and Siena. The earliest departure is at 11:35 AM in the morning, and the last departure from Isernia is at 11:35 AM which arrives into Siena at 5:10 PM. All services require a transfer, and take on average 5h 35m. The schedules shown below are for the next available departures.
Want to know about travelling from Isernia to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Isernia to Siena. However, there are services departing from Isernia station and arriving at Siena station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 5h 35m.
Isernia to Siena bus services, operated by FlixBus, depart from Isernia station.
Isernia to Siena bus services, operated by FlixBus, arrive at Siena station.
Book your Isernia to Siena bus tickets online with FlixBus.
The distance between Isernia and Siena is 305.6 km. The road distance is 406 km.
You can take a bus from Isernia to Siena via Roma, Autostazione Tiburtina in around 6h 5m.
