Islip to Holtsville Buses

Islip to Holtsville buses

Travel from

Search accommodation with Expedia

Trip Overview

The average bus between Islip and Holtsville takes 1h 20m and the fastest bus takes 51 min. There is a bus service every few hours from Islip to Holtsville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

1h 20m
Duration: 18 mi
Distance: $5
Average price: Hourly
Frequency

Line 2 bus, line 53 bus

best

Take the bus from Islip Town Hall to Patchogue LIRRbus 2
Take the bus from Patchogue LIRR to Waverly Ave/Long Island Avebus 53

1h 30m

Islip to Holtsville bus times

Buses run hourly between Islip and Holtsville. The earliest departure is at 5:56 AM in the morning, and the last departure from Islip is at 10:55 PM which arrives into Holtsville at 5:49 AM. All services require a transfer, and take on average 1h 20m. The schedules shown below are for the next available departures.

Departing Friday, October 30, 2026

7:56 AM → 8:49 AM
53 min • 1 change
8:56 AM → 9:47 AM
51 min • 1 change
9:56 AM → 10:48 AM
52 min • 1 change
10:27 AM → 11:48 AM
1h 21m • 1 change
Show more

Departing Saturday, October 31, 2026

6:52 AM → 7:49 AM
57 min • 1 change
7:52 AM → 8:49 AM
57 min • 1 change
8:52 AM → 9:49 AM
57 min • 1 change
9:52 AM → 10:49 AM
57 min • 1 change
Show more

Departing Sunday, November 1, 2026

6:54 AM → 7:49 AM
55 min • 1 change
7:54 AM → 8:49 AM
55 min • 1 change
8:54 AM → 9:49 AM
55 min • 1 change
9:54 AM → 10:49 AM
55 min • 1 change
Show more

Departing Monday, November 2, 2026

5:56 AM → 6:49 AM
53 min • 1 change
6:56 AM → 7:49 AM
53 min • 1 change
7:56 AM → 8:49 AM
53 min • 1 change
8:56 AM → 9:47 AM
51 min • 1 change
Show more

Departing Tuesday, November 3, 2026

5:56 AM → 6:49 AM
53 min • 1 change
6:56 AM → 7:49 AM
53 min • 1 change
7:56 AM → 8:49 AM
53 min • 1 change
8:56 AM → 9:47 AM
51 min • 1 change
Show more

Departing Wednesday, November 4, 2026

5:56 AM → 6:49 AM
53 min • 1 change
6:56 AM → 7:49 AM
53 min • 1 change
7:56 AM → 8:49 AM
53 min • 1 change
8:56 AM → 9:47 AM
51 min • 1 change
Show more

Departing Thursday, November 5, 2026

5:56 AM → 6:49 AM
53 min • 1 change
6:56 AM → 7:49 AM
53 min • 1 change
7:56 AM → 8:49 AM
53 min • 1 change
8:56 AM → 9:47 AM
51 min • 1 change
Show more

Frequently asked questions

Want to know about travelling from Islip to Holtsville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Find Transport to Holtsville

Trip Overview

Line 2 bus, line 53 bus

Islip to Holtsville bus times

Departing Friday, October 30, 2026

7:56 AM → 8:49 AM

8:56 AM → 9:47 AM

9:56 AM → 10:48 AM

10:27 AM → 11:48 AM

Departing Saturday, October 31, 2026

6:52 AM → 7:49 AM

7:52 AM → 8:49 AM

8:52 AM → 9:49 AM

9:52 AM → 10:49 AM

Departing Sunday, November 1, 2026

6:54 AM → 7:49 AM

7:54 AM → 8:49 AM

8:54 AM → 9:49 AM

9:54 AM → 10:49 AM

Departing Monday, November 2, 2026

5:56 AM → 6:49 AM

6:56 AM → 7:49 AM

7:56 AM → 8:49 AM

8:56 AM → 9:47 AM

Departing Tuesday, November 3, 2026

5:56 AM → 6:49 AM

6:56 AM → 7:49 AM

7:56 AM → 8:49 AM

8:56 AM → 9:47 AM

Departing Wednesday, November 4, 2026

5:56 AM → 6:49 AM

6:56 AM → 7:49 AM

7:56 AM → 8:49 AM

8:56 AM → 9:47 AM

Departing Thursday, November 5, 2026

5:56 AM → 6:49 AM

6:56 AM → 7:49 AM

7:56 AM → 8:49 AM

8:56 AM → 9:47 AM

Frequently asked questions

What companies run services between Islip, NY, USA and Holtsville, NY, USA?

Bus from Islip Town Hall to Patchogue LIRR

Bus from Patchogue LIRR to Waverly Ave/Long Island Ave

Bus trips from Islip

Bus trips to Holtsville

Alternative transport options