The average bus between Isola Ortigia and Milazzo takes 3h 32m and the fastest bus takes 3h 25m. The bus service runs several times per day from Isola Ortigia to Milazzo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Isola Ortigia and Milazzo. The earliest departure is at 7:05 AM in the morning, and the last departure from Isola Ortigia is at 7:35 PM which arrives into Milazzo at 11:00 PM. All services require a transfer, and take on average 3h 32m. The schedules shown below are for the next available departures.

3h 25m • 1 change

3h 40m • 1 change

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3h 55m • 1 change

3h 25m • 1 change

3h 25m • 1 change

3h 25m • 1 change

3h 55m • 1 change

3h 25m • 1 change

3h 25m • 1 change

3h 25m • 1 change

3h 55m • 1 change

3h 25m • 1 change

3h 25m • 1 change

3h 25m • 1 change

3h 55m • 1 change

3h 25m • 1 change

3h 25m • 1 change

3h 25m • 1 change
Want to know about travelling from Isola Ortigia to Milazzo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Isola Ortigia to Milazzo. However, there are services departing from Isola Ortigia station and arriving at Milazzo station via Catania Airport. The journey, including transfers, takes approximately 3h 32m.
Isola Ortigia to Milazzo bus services, operated by Interbus, depart from Siracusa - Corso Gelone station.
Isola Ortigia to Milazzo bus services, operated by Interbus, arrive at Milazzo Port Stop station.
Book your Isola Ortigia to Milazzo bus tickets online with Interbus and Giuntabus.
The distance between Isola Ortigia and Milazzo is 129 km. The road distance is 198 km.
You can take a bus from Siracusa - Corso Gelone to Milazzo Port Stop via Catania Airport in around 4h 10m.