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Isola Ortigia to Palermo buses

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Trip Overview

The average bus between Isola Ortigia and Palermo takes 4h 35m and the fastest bus takes 3h 55m. The bus service runs several times per day from Isola Ortigia to Palermo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 35m
Duration
268 km
Distance
€21
Average price
Twice daily
Frequency

Isola Ortigia to Palermo bus times

Buses run twice daily between Isola Ortigia and Palermo. The earliest departure is at 7:05 AM in the morning, and the last departure from Isola Ortigia is at 2:05 PM which arrives into Palermo at 7:20 PM. All services require a transfer at Catania Airport and take an average of 4h 35m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

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    InterbusFlixBus5h 15m • 1 change

Departing Monday, November 9, 2026

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    InterbusFlixBus3h 55m • 1 change
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    InterbusFlixBus5h 15m • 1 change

Departing Tuesday, November 10, 2026

  •  → 

    InterbusFlixBus3h 55m • 1 change
  •  → 

    InterbusFlixBus5h 15m • 1 change

Departing Wednesday, November 11, 2026

  •  → 

    InterbusFlixBus3h 55m • 1 change
  •  → 

    InterbusFlixBus5h 15m • 1 change

Departing Thursday, November 12, 2026

  •  → 

    InterbusFlixBus3h 55m • 1 change
  •  → 

    InterbusFlixBus5h 15m • 1 change

Departing Friday, November 13, 2026

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    InterbusFlixBus3h 55m • 1 change
  •  → 

    InterbusFlixBus5h 15m • 1 change

Departing Saturday, November 14, 2026

  •  → 

    InterbusFlixBus3h 55m • 1 change
  •  → 

    InterbusFlixBus5h 15m • 1 change

Frequently asked questions

Want to know about travelling from Isola Ortigia to Palermo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Isola Ortigia to Palermo.ExpandLaunch map view
  • Distance: 267.9 km
  • Duration: 4h 35m

What companies run services between Isola Ortigia, Italy and Palermo, Italy?

You can take a bus from Siracusa - Corso Gelone to Palermo Via Tommaso Fazello via Catania Airport and Catania Fontanarossa Airport Bus Stop in around 4h 40m.

Operators