Issy-les-Moulineaux to Lyon Buses

Issy-les-Moulineaux to Lyon buses

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Trip Overview

The average bus between Issy-les-Moulineaux and Lyon takes 6h 50m and the fastest bus takes 6h 25m. There is a bus service every few hours from Issy-les-Moulineaux to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

6h 50m
Duration: 475 km
Distance: €40
Average price: Hourly
Frequency

Bus

best

Take the bus from Paris - Bercy-Seine Bus Station to Lyon - Gerland Bus Stationbus BlaBlaCar Bus

6h 49m

€24–60

Issy-les-Moulineaux to Lyon bus times

Buses run hourly between Issy-les-Moulineaux and Lyon. The earliest departure is at 6:41 AM in the morning, and the last departure from Issy-les-Moulineaux is at 10:31 PM which arrives into Lyon at 5:20 AM. All services require a transfer at Quai de la Gare and take an average of 6h 50m. The schedules shown below are for the next available departures.

Departing Friday, October 9, 2026

9:04 AM → 4:25 PM
7h 21m • 1 change
11:35 AM → 6:50 PM
7h 15m • 1 change
12:02 PM → 7:10 PM
7h 8m • 1 change
4:12 PM → 9:20 PM
7h 8m • 1 change
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Departing Saturday, October 10, 2026

6:50 AM → 1:40 PM
6h 50m • 1 change
7:14 AM → 2:00 PM
6h 46m • 1 change
8:15 AM → 2:40 PM
6h 25m • 1 change
9:16 AM → 4:25 PM
7h 9m • 1 change
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Departing Sunday, October 11, 2026

6:41 AM → 1:40 PM
6h 59m • 1 change
7:02 AM → 2:00 PM
6h 58m • 1 change
8:08 AM → 2:40 PM
6h 32m • 1 change
9:13 AM → 4:25 PM
7h 12m • 1 change
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Frequently asked questions

Want to know about travelling from Issy-les-Moulineaux to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Issy-les-Moulineaux to Lyon buses

Trip Overview

Bus