Issy-les-Moulineaux to Lyon Buses

Issy-les-Moulineaux to Lyon buses

Travel from

Search accommodation with Expedia

Trip Overview

The average bus between Issy-les-Moulineaux and Lyon takes 6h 53m and the fastest bus takes 6h 25m. There is a bus service every few hours from Issy-les-Moulineaux to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

6h 53m
Duration: 475 km
Distance: €40
Average price: Hourly
Frequency

Bus

best

Take the bus from Paris - Bercy-Seine Bus Station to Lyon - Gerland Bus Stationbus BlaBlaCar Bus

6h 49m

€24–60

Issy-les-Moulineaux to Lyon bus times

Buses run hourly between Issy-les-Moulineaux and Lyon. The earliest departure is at 6:41 AM in the morning, and the last departure from Issy-les-Moulineaux is at 10:31 PM which arrives into Lyon at 5:20 AM. All services require a transfer at Quai de la Gare and take an average of 6h 53m. The schedules shown below are for the next available departures.

Departing Monday, October 12, 2026

4:12 PM → 9:20 PM
7h 8m • 1 change
5:05 PM → 11:50 PM
6h 45m • 1 change
5:41 PM → 12:20 AM
Arrives next day
6h 39m • 1 change
6:17 PM → 12:50 AM
Arrives next day
6h 33m • 1 change
Show more

Departing Tuesday, October 13, 2026

6:41 AM → 1:40 PM
6h 59m • 1 change
7:12 AM → 2:00 PM
6h 48m • 1 change
8:09 AM → 2:40 PM
6h 31m • 1 change
9:04 AM → 4:25 PM
7h 21m • 1 change
Show more

Departing Wednesday, October 14, 2026

6:41 AM → 1:40 PM
6h 59m • 1 change
7:12 AM → 2:00 PM
6h 48m • 1 change
8:09 AM → 2:40 PM
6h 31m • 1 change
9:04 AM → 4:25 PM
7h 21m • 1 change
Show more

Departing Thursday, October 15, 2026

6:41 AM → 1:40 PM
6h 59m • 1 change
7:12 AM → 2:00 PM
6h 48m • 1 change
8:09 AM → 2:40 PM
6h 31m • 1 change
9:04 AM → 4:25 PM
7h 21m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Issy-les-Moulineaux to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Issy-les-Moulineaux to Lyon buses

Trip Overview

Bus