The average bus between Istanbul and Eskişehir takes 6h 5m and the fastest bus takes 5h 30m. The bus service runs several times per day from Istanbul to Eskişehir. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Istanbul and Eskişehir. The earliest departure is at 3:00 AM at night, and the last departure from Istanbul is at 3:00 PM which arrives into Eskişehir at 9:00 PM. All services require a transfer at Bursa and take an average of 6h 5m. The schedules shown below are for the next available departures.

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Want to know about travelling from Istanbul to Eskişehir? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Istanbul to Eskişehir. However, there are services departing from Istanbul station and arriving at Eskişehir station via Bursa. The journey, including transfers, takes approximately 6h 5m.
Istanbul to Eskişehir bus services, operated by Pamukkale Turizm, depart from Esenler Otogar station.
Istanbul to Eskişehir bus services, operated by Pamukkale Turizm, arrive at Eskişehir TCDD train station.
Book your Istanbul to Eskişehir bus tickets online with Pamukkale Turizm, Kamil Koç and Kale Seyahat.
The distance between Istanbul and Eskişehir is 191.4 km. The road distance is 315 km.
You can take a bus from Esenler Otogar to Eskişehir TCDD train station via Bursa and Bursa bus station in around 5h 6m.