Istres to Lyon Buses

Istres to Lyon buses

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Trip Overview

The average bus between Istres and Lyon takes 7h 26m and the fastest bus takes 5h 38m. The bus service runs several times per day from Istres to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

7h 26m
Duration: 378 km
Distance: €44
Average price: Every 4 hours
Frequency

Bus

best

Take the bus from Marseille - Saint-Charles Bus Station to Lyon - Gerland Bus Stationbus BlaBlaCar Bus

6h 41m

€32–56

Istres to Lyon bus times

Buses run every 4 hours between Istres and Lyon. The earliest departure is at 7:04 AM in the morning, and the last departure from Istres is at 8:14 PM which arrives into Lyon at 11:50 AM. All services require a transfer at Pem Mtg and take an average of 7h 26m. The schedules shown below are for the next available departures.

Departing Sunday, November 1, 2026

10:51 AM → 6:00 PM
7h 9m • 2 changes
2:35 PM → 9:00 PM
6h 25m • 2 changes
4:31 PM → 11:45 PM
7h 14m • 2 changes
5:45 PM → 12:50 AM
Arrives next day
7h 5m • 2 changes

Departing Monday, November 2, 2026

7:04 AM → 11:50 AM
5h 46m • 2 changes
7:23 AM → 2:20 PM
6h 57m • 2 changes
8:54 AM → 3:20 PM
6h 26m • 2 changes
11:30 AM → 6:00 PM
6h 30m • 2 changes
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Departing Tuesday, November 3, 2026

7:04 AM → 11:50 AM
5h 46m • 2 changes
7:23 AM → 2:20 PM
6h 57m • 2 changes
8:54 AM → 3:20 PM
6h 26m • 2 changes
11:30 AM → 6:00 PM
6h 30m • 2 changes
Show more

Departing Wednesday, November 4, 2026

7:23 AM → 2:20 PM
6h 57m • 2 changes
8:54 AM → 3:20 PM
6h 26m • 2 changes
11:30 AM → 6:00 PM
6h 30m • 2 changes
2:30 PM → 9:00 PM
6h 29m • 2 changes
Show more

Departing Thursday, November 5, 2026

7:23 AM → 2:20 PM
6h 57m • 2 changes
8:54 AM → 3:20 PM
6h 26m • 2 changes
11:30 AM → 6:00 PM
6h 30m • 2 changes
2:30 PM → 9:00 PM
6h 29m • 2 changes
Show more

Departing Friday, November 6, 2026

7:04 AM → 11:50 AM
5h 46m • 2 changes
7:23 AM → 2:20 PM
6h 57m • 2 changes
8:54 AM → 3:20 PM
6h 26m • 2 changes
11:30 AM → 6:00 PM
6h 30m • 2 changes
Show more

Departing Saturday, November 7, 2026

7:28 AM → 2:20 PM
6h 52m • 2 changes
8:59 AM → 3:20 PM
6h 21m • 2 changes
10:52 AM → 6:00 PM
7h 8m • 2 changes
2:54 PM → 9:00 PM
6h 6m • 2 changes
Show more

Frequently asked questions

Want to know about travelling from Istres to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.