Istres to Lyon Buses

Istres to Lyon buses

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Trip Overview

The average bus between Istres and Lyon takes 5h 54m and the fastest bus takes 5h 11m. The bus service runs several times per day from Istres to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 54m
Duration: 353 km
Distance: €38
Average price: 4 times a day
Frequency

Bus

best

Take the bus from Aix-en-Provence - Krypton Park & Ride to Lyon - Gerland Bus Stationbus BlaBlaCar Bus

6h 33m

€26–50

Istres to Lyon bus times

Buses run 4 times a day between Istres and Lyon. The earliest departure is at 6:37 AM in the morning, and the last departure from Istres is at 6:49 PM which arrives into Lyon at 12:20 AM. All services require a transfer at Gare Routière and take an average of 5h 54m. The schedules shown below are for the next available departures.

Departing Monday, October 12, 2026

6:37 AM → 1:15 PM
6h 38m • 2 changes
8:56 AM → 3:00 PM
6h 4m • 2 changes
10:38 AM → 3:50 PM
5h 12m • 2 changes
11:24 AM → 6:35 PM
7h 11m • 2 changes
Show more

Departing Tuesday, October 13, 2026

8:56 AM → 3:20 PM
6h 24m • 2 changes
10:38 AM → 3:50 PM
5h 12m • 2 changes
3:40 PM → 9:00 PM
5h 20m • 2 changes
6:49 PM → 12:20 AM
Arrives next day
5h 31m • 2 changes

Departing Wednesday, October 14, 2026

8:56 AM → 3:20 PM
6h 24m • 2 changes
10:38 AM → 3:50 PM
5h 12m • 2 changes
3:40 PM → 9:00 PM
5h 20m • 2 changes
6:49 PM → 12:20 AM
Arrives next day
5h 31m • 2 changes

Departing Thursday, October 15, 2026

8:56 AM → 3:20 PM
6h 24m • 2 changes
10:38 AM → 3:50 PM
5h 12m • 2 changes
3:40 PM → 9:00 PM
5h 20m • 2 changes
6:49 PM → 12:20 AM
Arrives next day
5h 31m • 2 changes

Departing Friday, October 16, 2026

6:37 AM → 1:15 PM
6h 38m • 2 changes
8:56 AM → 3:20 PM
6h 24m • 2 changes
10:38 AM → 3:50 PM
5h 12m • 2 changes
3:40 PM → 9:00 PM
5h 20m • 2 changes
Show more

Departing Saturday, October 17, 2026

8:17 AM → 3:20 PM
7h 3m • 2 changes
10:39 AM → 3:50 PM
5h 11m • 2 changes
1:27 PM → 9:00 PM
7h 33m • 2 changes
6:09 PM → 12:20 AM
Arrives next day
6h 11m • 2 changes

Departing Sunday, October 18, 2026

8:34 AM → 3:20 PM
6h 46m • 2 changes
10:02 AM → 3:50 PM
5h 48m • 2 changes
3:02 PM → 9:00 PM
5h 58m • 2 changes
6:02 PM → 12:20 AM
Arrives next day
6h 18m • 2 changes

Frequently asked questions

Want to know about travelling from Istres to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Find Transport to Lyon

Trip Overview

Bus

Istres to Lyon bus times

Departing Monday, October 12, 2026

6:37 AM → 1:15 PM

8:56 AM → 3:00 PM

10:38 AM → 3:50 PM

11:24 AM → 6:35 PM

Departing Tuesday, October 13, 2026

8:56 AM → 3:20 PM

10:38 AM → 3:50 PM

3:40 PM → 9:00 PM

6:49 PM → 12:20 AMArrives next day

Departing Wednesday, October 14, 2026

8:56 AM → 3:20 PM

10:38 AM → 3:50 PM

3:40 PM → 9:00 PM

6:49 PM → 12:20 AMArrives next day

Departing Thursday, October 15, 2026

8:56 AM → 3:20 PM

10:38 AM → 3:50 PM

3:40 PM → 9:00 PM

6:49 PM → 12:20 AMArrives next day

Departing Friday, October 16, 2026

6:37 AM → 1:15 PM

8:56 AM → 3:20 PM

10:38 AM → 3:50 PM

3:40 PM → 9:00 PM

Departing Saturday, October 17, 2026

8:17 AM → 3:20 PM

10:39 AM → 3:50 PM

1:27 PM → 9:00 PM

6:09 PM → 12:20 AMArrives next day

Departing Sunday, October 18, 2026

8:34 AM → 3:20 PM

10:02 AM → 3:50 PM

3:02 PM → 9:00 PM

6:02 PM → 12:20 AMArrives next day

Frequently asked questions

What companies run services between Istres, France and Lyon, France?

Bus from Aix-en-Provence - Krypton Park & Ride to Lyon - Gerland Bus Station

Where to next?

Bus trips from Istres

Bus trips to Lyon

Alternative transport options

6:49 PM → 12:20 AM
Arrives next day

6:49 PM → 12:20 AM
Arrives next day

6:49 PM → 12:20 AM
Arrives next day

6:09 PM → 12:20 AM
Arrives next day

6:02 PM → 12:20 AM
Arrives next day