Rome2Rio

Italy to Santander buses

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Trip Overview

The average bus between Italy and Santander takes 45h 2m and the fastest bus takes 39h 40m. The bus runs, on average, 2 times per week from Italy to Santander. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

45h 2m
Duration
1,887 km
Distance
€208
Average price
Twice a week
Frequency

Italy to Santander bus times

Buses run twice a week between Italy and Santander. The earliest departure is at 5:35 AM in the morning, and the last departure from Italy is at 4:20 PM which arrives into Santander at 8:00 AM. All services require a transfer at Roma, Autostazione Tiburtina and take an average of 45h 2m. The schedules shown below are for the next available departures.

Departing Monday, November 2, 2026

  •  → 

    Arrives +2 days

    ATAC S.p.A. Azienda per la mobilitàFlixBusFlixBusALSA39h 40m • 3 changes

Departing Wednesday, November 4, 2026

  •  → 

    Arrives +2 days

    ATAC S.p.A. Azienda per la mobilitàFlixBusFlixBusALSA2d 2h • 3 changes

Frequently asked questions

Want to know about travelling from Italy to Santander? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Italy to Santander.ExpandLaunch map view
  • Distance: 1,887.3 km
  • Duration: 45h 2m

What companies run services between Italy and Santander, Spain?

You can take a bus from Termini to Estación de autobuses de Santander via Roma, Autostazione Tiburtina, Toulon, Bilbao, and Bilbao Intermodal in around 30h 2m.

Operators