Rome2Rio

Italy to Spain buses

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Trip Overview

The average bus between Italy and Spain takes 28h 40m and the fastest bus takes 27h 15m. There is at least one bus per day from Italy to Spain. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

28h 40m
Duration
1,389 km
Distance
€135
Average price
Once daily
Frequency

Italy to Spain bus times

Buses run once daily between Italy and Spain. The earliest departure is at 12:44 AM at night, and the last departure from Italy is at 7:00 AM which arrives into Spain at 10:15 AM. All services require a transfer at Rome Tiburtina Largo Mazzoni and take an average of 28h 40m. The schedules shown below are for the next available departures.

Departing Wednesday, November 4, 2026

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    Arrives next day

    Cotral S.p.A.FlixBusFlixBusBlaBlaCar Bus27h 29m • 3 changes

Departing Thursday, November 5, 2026

  •  → 

    Arrives next day

    Cotral S.p.A.FlixBusFlixBusBlaBlaCar Bus27h 29m • 3 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives next day

    Cotral S.p.A.FlixBusFlixBusBlaBlaCar Bus27h 29m • 3 changes

Departing Saturday, November 7, 2026

  •  → 

    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBusFlixBusBlaBlaCar Bus27h 15m • 3 changes

Departing Sunday, November 8, 2026

  •  → 

    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBusFlixBusBlaBlaCar Bus27h 15m • 3 changes

Departing Monday, November 9, 2026

  •  → 

    Arrives next day

    ATAC S.p.A. Azienda per la mobilitàFlixBusFlixBusBlaBlaCar Bus33h 30m • 3 changes

Departing Tuesday, November 10, 2026

  •  → 

    Arrives next day

    Cotral S.p.A.FlixBusFlixBusALSA30h 14m • 3 changes

Frequently asked questions

Want to know about travelling from Italy to Spain? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Italy to Spain.ExpandLaunch map view
  • Distance: 1,388.6 km
  • Duration: 28h 40m

What companies run services between Italy and Spain?

You can take a bus from Termini to Barcelona - North Bus Station via Rome Tiburtina Largo Mazzoni, Florence, and Perpignan - Bus Station in around 20h 29m.

Operators