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Ithaca to Mechanicsburg buses

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Trip Overview

The average bus between Ithaca and Mechanicsburg takes 34h 16m and the fastest bus takes 32h 28m. The bus runs, on average, 5 times per week from Ithaca to Mechanicsburg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

34h 16m
Duration
240 mi
Distance
$92
Average price
5 times a week
Frequency

Ithaca to Mechanicsburg bus times

Buses run 5 times a week between Ithaca and Mechanicsburg. The earliest departure is at 7:15 PM in the evening, and the last departure from Ithaca is at 9:30 PM which arrives into Mechanicsburg at 5:58 AM. All services require a transfer at Binghamton and take an average of 34h 16m. The schedules shown below are for the next available departures.

Departing Saturday, October 10, 2026

  •  → 

    Arrives +2 days

    Flixbus USAGreyhound USATrailwaysRabbit Transit34h 43m • 3 changes

Departing Sunday, October 11, 2026

  •  → 

    Arrives +2 days

    Flixbus USAGreyhound USATrailwaysRabbit Transit34h 43m • 3 changes

Departing Monday, October 12, 2026

  •  → 

    Arrives +2 days

    Flixbus USAGreyhound USATrailwaysRabbit Transit34h 43m • 3 changes

Departing Tuesday, October 13, 2026

  •  → 

    Arrives +2 days

    Flixbus USAGreyhound USATrailwaysRabbit Transit32h 28m • 3 changes

Departing Wednesday, October 14, 2026

  •  → 

    Arrives +2 days

    Flixbus USAGreyhound USATrailwaysRabbit Transit34h 43m • 3 changes

Frequently asked questions

Want to know about travelling from Ithaca to Mechanicsburg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Ithaca to Mechanicsburg.ExpandLaunch map view
  • Distance: 240.1 mi
  • Duration: 34h 16m

What companies run services between Ithaca, NY, USA and Mechanicsburg, Cumberland County, PA, USA?

You can take a bus from Ithaca to E Main St & Arch St WB via Binghamton, Scranton, Pa, Harrisburg, Pa, and Market Square Transfer Center in around 8h 29m.

Operators