The average bus between Jacksonville (Station) and Florida Keys takes 22h 16m and the fastest bus takes 21h 10m. The bus runs, on average, 6 times per week from Jacksonville (Station) to Florida Keys. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 6 times a week between Jacksonville (Station) and Florida Keys. The earliest departure is at 9:44 AM in the morning, and the last departure from Jacksonville (Station) is at 3:05 PM which arrives into Florida Keys at 12:15 PM. All services require a transfer at Amtrak Station and take an average of 22h 16m. The schedules shown below are for the next available departures.
Want to know about travelling from Jacksonville (Station) to Florida Keys? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Jacksonville (Station) to Florida Keys. However, there are services departing from Jacksonville station and arriving at Big Pine Key station via Miami Airport Station. The journey, including transfers, takes approximately 22h 16m.
Jacksonville (Station) to Florida Keys bus services, operated by Flixbus USA, depart from Jacksonville station.
Jacksonville (Station) to Florida Keys bus services, operated by Greyhound USA, arrive at Big Pine Key station.
The distance between Jacksonville (Station) and Florida Keys is 636.2 km. The road distance is 792 km.
You can take a vehicle from Jacksonville (Station) to Florida Keys via Amtrak Station, JRTC Bay H, Jacksonville, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 17h.