The average bus between Jacksonville and Florida Keys takes 22h 45m and the fastest bus takes 20h 30m. There is at least one bus per day from Jacksonville to Florida Keys. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Jacksonville and Florida Keys. The earliest departure is at 10:30 AM in the morning, and the last departure from Jacksonville is at 3:45 PM which arrives into Florida Keys at 12:15 PM. All services require a transfer at Miami Airport Station and take an average of 22h 45m. The schedules shown below are for the next available departures.
Want to know about travelling from Jacksonville to Florida Keys? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Jacksonville to Florida Keys. However, there are services departing from Jacksonville station and arriving at Florida Keys station via Miami Airport Station station. The journey, including transfers, takes approximately 22h 45m.
Jacksonville to Florida Keys bus services, operated by Flixbus USA, depart from Jacksonville station.
Jacksonville to Florida Keys bus services, operated by Flixbus USA, arrive at Big Pine Key station.
The distance between Jacksonville and Florida Keys is 632.4 km. The road distance is 894 km.
You can take a bus from Jacksonville to Florida Keys via Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 15h 25m.
