The average bus between Jacksonville and St. Louis takes 22h 45m and the fastest bus takes 17h 50m. The bus service runs several times per day from Jacksonville to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Jacksonville and St. Louis. The earliest departure is at 4:30 PM in the afternoon, and the last departure from Jacksonville is at 9:25 PM which arrives into St. Louis at 9:30 PM. All services require a transfer, and take on average 22h 45m. The schedules shown below are for the next available departures.
Want to know about travelling from Jacksonville to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Jacksonville to St. Louis. However, there are services departing from Jacksonville station and arriving at St Louis Bus Station via Atlanta Bus Station. The journey, including transfers, takes approximately 22h 45m.
Jacksonville to St. Louis bus services, operated by Flixbus USA, depart from Jacksonville station.
Jacksonville to St. Louis bus services, operated by Flixbus USA, arrive at St Louis Bus Station.
Book your Jacksonville to St. Louis bus tickets online with Omio and FlixBus.
The distance between Jacksonville and St. Louis is 1208.7 km. The road distance is 1386 km.
You can take a bus from Jacksonville to St Louis Bus Station via Atlanta Bus Station in around 18h 1m.
