The average bus between Kalamazoo and Louisville takes 21h 21m and the fastest bus takes 17h 50m. The bus service runs several times per day from Kalamazoo to Louisville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Kalamazoo and Louisville. The earliest departure is at 12:10 PM in the afternoon, and the last departure from Kalamazoo is at 7:30 PM which arrives into Louisville at 6:20 PM. All services require a transfer at Gary Bus Station and take an average of 21h 21m. The schedules shown below are for the next available departures.
Arrives next day


17h 50m • 2 changes
Arrives next day


22h 50m • 2 changes
Arrives next day


17h 50m • 2 changes
Arrives next day


22h 50m • 2 changes
Want to know about travelling from Kalamazoo to Louisville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Kalamazoo to Louisville. However, there are services departing from Kalamazoo station and arriving at Louisville station via Gary Bus Station station. The journey, including transfers, takes approximately 21h 21m.
Kalamazoo to Louisville bus services, operated by Greyhound USA, depart from Kalamazoo Bus Stop station.
Kalamazoo to Louisville bus services, operated by Greyhound USA, arrive at Louisville, KY station.
Book your Kalamazoo to Louisville bus tickets online with Greyhound USA and Amtrak Thruway.
The distance between Kalamazoo and Louisville is 449.2 km. The road distance is 614 km.
You can take a bus from Kalamazoo Bus Stop to Louisville, KY via Gary Bus Station and Indianapolis Union Station in around 9h.