Karlovy Vary to Brno Buses

Karlovy Vary to Brno buses

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Trip Overview

The average bus between Karlovy Vary and Brno takes 5h and the fastest bus takes 4h 35m. The bus service runs several times per day from Karlovy Vary to Brno. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h
Duration: 346 km
Distance: Kč 885
Average price: Every 3 hours
Frequency

Bus via Prague

best

Take the bus from Karlovy Vary to Praha, ÚAN Florencbus 854 / ...
Take the bus from Praha, ÚAN Florenc to Brnobus 850 / ...

5h 22m

Kč 615–1,116

Karlovy Vary to Brno bus times

Buses run every 3 hours between Karlovy Vary and Brno. The earliest departure is at 5:30 AM in the morning, and the last departure from Karlovy Vary is at 8:30 PM which arrives into Brno at 1:55 AM. All services require a transfer, and take on average 5h. The schedules shown below are for the next available departures.

Departing Monday, November 2, 2026

2:30 PM → 7:25 PM
4h 55m • 1 change
4:00 PM → 8:40 PM
4h 40m • 1 change
4:10 PM → 9:00 PM
4h 50m • 1 change
6:30 PM → 11:20 PM
4h 50m • 1 change

Departing Tuesday, November 3, 2026

6:15 AM → 12:10 PM
5h 55m • 1 change
7:35 AM → 12:40 PM
5h 5m • 1 change
9:30 AM → 2:05 PM
4h 35m • 1 change
12:30 PM → 5:10 PM
4h 40m • 1 change
Show more

Departing Wednesday, November 4, 2026

6:15 AM → 12:10 PM
5h 55m • 1 change
7:35 AM → 12:40 PM
5h 5m • 1 change
9:30 AM → 2:05 PM
4h 35m • 1 change
12:30 PM → 5:10 PM
4h 40m • 1 change
Show more

Departing Thursday, November 5, 2026

6:15 AM → 12:10 PM
5h 55m • 1 change
7:35 AM → 12:40 PM
5h 5m • 1 change
9:30 AM → 2:05 PM
4h 35m • 1 change
12:30 PM → 5:10 PM
4h 40m • 1 change
Show more

Departing Friday, November 6, 2026

6:15 AM → 12:10 PM
5h 55m • 1 change
7:35 AM → 12:40 PM
5h 5m • 1 change
9:30 AM → 2:05 PM
4h 35m • 1 change
12:30 PM → 5:10 PM
4h 40m • 1 change
Show more

Departing Saturday, November 7, 2026

5:30 AM → 10:30 AM
5h • 1 change
6:15 AM → 12:10 PM
5h 55m • 1 change
7:35 AM → 12:40 PM
5h 5m • 1 change
9:30 AM → 2:05 PM
4h 35m • 1 change
Show more

Departing Sunday, November 8, 2026

5:30 AM → 10:30 AM
5h • 1 change
6:15 AM → 12:10 PM
5h 55m • 1 change
7:35 AM → 12:40 PM
5h 5m • 1 change
9:30 AM → 2:05 PM
4h 35m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Karlovy Vary to Brno? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Find Transport to Brno

Trip Overview

Bus via Prague

Karlovy Vary to Brno bus times

Departing Monday, November 2, 2026

2:30 PM → 7:25 PM

4:00 PM → 8:40 PM

4:10 PM → 9:00 PM

6:30 PM → 11:20 PM

Departing Tuesday, November 3, 2026

6:15 AM → 12:10 PM

7:35 AM → 12:40 PM

9:30 AM → 2:05 PM

12:30 PM → 5:10 PM

Departing Wednesday, November 4, 2026

6:15 AM → 12:10 PM

7:35 AM → 12:40 PM

9:30 AM → 2:05 PM

12:30 PM → 5:10 PM

Departing Thursday, November 5, 2026

6:15 AM → 12:10 PM

7:35 AM → 12:40 PM

9:30 AM → 2:05 PM

12:30 PM → 5:10 PM

Departing Friday, November 6, 2026

6:15 AM → 12:10 PM

7:35 AM → 12:40 PM

9:30 AM → 2:05 PM

12:30 PM → 5:10 PM

Departing Saturday, November 7, 2026

5:30 AM → 10:30 AM

6:15 AM → 12:10 PM

7:35 AM → 12:40 PM

9:30 AM → 2:05 PM

Departing Sunday, November 8, 2026

5:30 AM → 10:30 AM

6:15 AM → 12:10 PM

7:35 AM → 12:40 PM

9:30 AM → 2:05 PM

Frequently asked questions

What companies run services between Karlovy Vary, Czechia and Brno, Czechia?

Bus from Karlovy Vary to Praha, ÚAN Florenc

Bus from Praha, ÚAN Florenc to Brno

Bus from Karlovy Vary to Brno

Bus from Praha, ÚAN Florenc to Brno

Where to next?

Bus trips from Karlovy Vary

Bus trips to Brno

Alternative transport options