The average bus between Karlovy Vary and Košice takes 16h 9m and the fastest bus takes 12h 40m. The bus service runs several times per day from Karlovy Vary to Košice. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Karlovy Vary and Košice. The earliest departure is at 6:15 AM in the morning, and the last departure from Karlovy Vary is at 8:30 PM which arrives into Košice at 6:50 PM. All services require a transfer, and take on average 16h 9m. The schedules shown below are for the next available departures.

12h 40m • 1 change
Arrives next day

13h • 1 change
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22h 20m • 1 change

12h 40m • 1 change
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13h • 1 change
Arrives next day

22h 20m • 1 change

12h 40m • 1 change
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13h • 1 change
Arrives next day

22h 20m • 1 change

12h 40m • 1 change
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13h • 1 change
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24h 20m • 1 change
Want to know about travelling from Karlovy Vary to Košice? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Karlovy Vary to Košice. However, there are services departing from Karlovy Vary station and arriving at Košice station via Praha, ÚAN Florenc. The journey, including transfers, takes approximately 16h 9m.
Karlovy Vary to Košice bus services, operated by FlixBus, depart from Karlovy Vary station.
Karlovy Vary to Košice bus services, operated by FlixBus, arrive at Košice station.
Book your Karlovy Vary to Košice bus tickets online with FlixBus.
The distance between Karlovy Vary and Košice is 628.7 km. The road distance is 826 km.
You can take a bus from Karlovy Vary to Košice via Praha, ÚAN Florenc in around 13h 55m.