The average bus between Karlovy Vary and Lyon takes 20h 20m and the fastest bus takes 18h 10m. The bus service runs several times per day from Karlovy Vary to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Karlovy Vary and Lyon. The earliest departure is at 12:30 PM in the afternoon, and the last departure from Karlovy Vary is at 8:30 PM which arrives into Lyon at 11:15 PM. All services require a transfer, and take on average 20h 20m. The schedules shown below are for the next available departures.
Arrives next day

19h 45m • 1 change
Arrives next day

18h 10m • 1 change
Arrives next day

19h 45m • 1 change
Arrives next day

18h 10m • 1 change
Arrives next day

19h 45m • 1 change
Arrives next day

18h 10m • 1 change
Arrives next day

26h 45m • 1 change
Arrives next day

19h 45m • 1 change
Arrives next day

18h 10m • 1 change
Arrives next day

26h 45m • 1 change
Arrives next day

19h 45m • 1 change
Arrives next day

18h 10m • 1 change
Arrives next day

26h 45m • 1 change
Want to know about travelling from Karlovy Vary to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Karlovy Vary to Lyon. However, there are services departing from Karlovy Vary station and arriving at Lyon station via Praha, ÚAN Florenc. The journey, including transfers, takes approximately 20h 20m.
Karlovy Vary to Lyon bus services, operated by FlixBus, depart from Karlovy Vary station.
Karlovy Vary to Lyon bus services, operated by FlixBus, arrive at Lyon station.
Book your Karlovy Vary to Lyon bus tickets online with FlixBus.
The distance between Karlovy Vary and Lyon is 777.2 km. The road distance is 1,228 km.
You can take a bus from Karlovy Vary to Lyon via Praha, ÚAN Florenc in around 18h 15m.