The average bus between Karlsruhe and Leverkusen takes 6h 3m and the fastest bus takes 5h 25m. The bus service runs several times per day from Karlsruhe to Leverkusen. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Karlsruhe and Leverkusen. The earliest departure is at 1:40 AM at night, and the last departure from Karlsruhe is at 11:55 PM which arrives into Leverkusen at 5:35 AM. All services require a transfer, and take on average 6h 3m. The schedules shown below are for the next available departures.

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5h 40m • 1 changeWant to know about travelling from Karlsruhe to Leverkusen? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Karlsruhe to Leverkusen. However, there are services departing from Karlsruhe central train station and arriving at Cologne Airport CGN station via Cologne Airport CGN station. The journey, including transfers, takes approximately 6h 3m.
Karlsruhe to Leverkusen bus services, operated by FlixBus, depart from Karlsruhe central train station.
Karlsruhe to Leverkusen bus services, operated by FlixBus, arrive at Cologne Airport CGN station.
Book your Karlsruhe to Leverkusen bus tickets online with Omio and FlixBus.
The distance between Karlsruhe and Leverkusen is 246.5 km. The road distance is 306 km.
FlixBus operates a bus from Karlsruhe central train station to Cologne Airport CGN every 4 hours. Tickets cost €26–40 and the journey takes 4h 25m.