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Karlsruhe to Mainz buses

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Trip Overview

The bus between Karlsruhe and Mainz takes 3h 50m. The bus runs, on average, 5 times per week from Karlsruhe to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 50m
Duration
185 km
Distance
€20
Average price
5 times a week
Frequency

Karlsruhe to Mainz bus times

Buses run 5 times a week between Karlsruhe and Mainz. The service departs Karlsruhe at 2:40 PM in the afternoon, which arrives into Mainz at 18:30:00. All services run direct with no transfers required, and take on average 3h 50m. The schedules shown below are for the next available departures.

Departing Monday, November 2, 2026

  •  → 

    bus bus 3h 50m • Direct

Departing Thursday, November 5, 2026

  •  → 

    bus bus 3h 50m • Direct

Departing Friday, November 6, 2026

  •  → 

    bus bus 3h 50m • Direct

Departing Saturday, November 7, 2026

  •  → 

    bus bus 3h 50m • Direct

Departing Sunday, November 8, 2026

  •  → 

    bus bus 3h 50m • Direct

Frequently asked questions

Want to know about travelling from Karlsruhe to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Karlsruhe to Mainz.ExpandLaunch map view
  • Distance: 185 km
  • Duration: 3h 50m

What companies run services between Karlsruhe, Germany and Mainz, Germany?

FlixBus operates a bus from Karlsruhe central train station to Mainz central train station once daily. Tickets cost €16–25 and the journey takes 3h 50m.

Operators