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Key Largo to Cape Coral buses

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Trip Overview

The average bus between Key Largo and Cape Coral takes 11h 52m and the fastest bus takes 7h. The bus service runs several times per day from Key Largo to Cape Coral. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

11h 52m
Duration
241 mi
Distance
$46
Average price
Twice daily
Frequency

Key Largo to Cape Coral bus times

Buses run twice daily between Key Largo and Cape Coral. The earliest departure is at 12:55 PM in the afternoon, and the last departure from Key Largo is at 8:00 PM which arrives into Cape Coral at 12:04 PM. All services require a transfer at Miami Airport Station and take an average of 11h 52m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

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    Arrives next day

    Greyhound USAFlixbus USALee County Transit16h 4m • 2 changes

Departing Wednesday, November 11, 2026

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    Greyhound USAFlixbus USALee County Transit7h • 2 changes
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    Arrives next day

    Greyhound USAFlixbus USALee County Transit16h 4m • 2 changes

Departing Thursday, November 12, 2026

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    Greyhound USAFlixbus USALee County Transit7h • 2 changes
  •  → 

    Arrives next day

    Greyhound USAFlixbus USALee County Transit16h 4m • 2 changes

Departing Friday, November 13, 2026

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    Greyhound USAFlixbus USALee County Transit7h • 2 changes
  •  → 

    Arrives next day

    Greyhound USAFlixbus USALee County Transit16h 4m • 2 changes

Departing Saturday, November 14, 2026

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    Greyhound USAFlixbus USALee County Transit7h • 2 changes
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    Arrives next day

    Greyhound USAFlixbus USALee County Transit15h 48m • 2 changes

Departing Sunday, November 15, 2026

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    Greyhound USAFlixbus USALee County Transit7h 13m • 2 changes
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    Arrives next day

    Greyhound USAFlixbus USALee County Transit16h 4m • 2 changes

Departing Monday, November 16, 2026

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    Greyhound USAFlixbus USALee County Transit7h • 2 changes

Frequently asked questions

Want to know about travelling from Key Largo to Cape Coral? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Key Largo to Cape Coral.ExpandLaunch map view
  • Distance: 240.9 mi
  • Duration: 11h 52m

What companies run services between Key Largo, FL, USA and Cape Coral, FL, USA?

You can take a bus from Key Largo Bus Stop to Cc Pwky @ Vincennes Blvd via Miami Airport Station and Rosa Parks Transportation Ctr in around 7h 8m.

Operators