The average bus between Key West (Island) and Louisville takes 34h 25m and the fastest bus takes 33h 55m. There is at least one bus per day from Key West (Island) to Louisville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Key West (Island) and Louisville. The earliest departure is at 5:00 PM in the evening, and the last departure from Key West (Island) is at 5:00 PM which arrives into Louisville at 2:55 AM. All services require a transfer at Miami Airport Station and take an average of 34h 25m. The schedules shown below are for the next available departures.
Want to know about travelling from Key West (Island) to Louisville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Key West (Island) to Louisville. However, there are services departing from Key West (Island) station and arriving at Louisville station via Miami Airport Station station. The journey, including transfers, takes approximately 34h 25m.
Key West (Island) to Louisville bus services, operated by Greyhound USA, depart from Key West Airport station.
Key West (Island) to Louisville bus services, operated by Greyhound USA, arrive at Louisville, KY station.
Book your Key West (Island) to Louisville bus tickets online with Greyhound USA and Amtrak Thruway.
The distance between Key West (Island) and Louisville is 1,568.7 km. The road distance is 2,022 km.
You can take a bus from Key West Airport to Louisville, KY via Miami Airport Station, Atlanta Bus Station, and Nashville in around 28h 15m.