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Key West (Island) to Orlando buses

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Trip Overview

The average bus between Key West (Island) and Orlando takes 11h 31m and the fastest bus takes 9h 30m. The bus service runs several times per day from Key West (Island) to Orlando. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

11h 31m
Duration
387 mi
Distance
$80
Average price
Twice daily
Frequency

Key West (Island) to Orlando bus times

Buses run twice daily between Key West (Island) and Orlando. The earliest departure is at 1:30 PM in the afternoon, and the last departure from Key West (Island) is at 5:00 PM which arrives into Orlando at 5:03 AM. All services require a transfer at Miami Airport Station and take an average of 11h 31m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

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    Arrives next day

    Greyhound USAFlixbus USALynx Central Florida Transport12h 3m • 2 changes

Departing Thursday, November 12, 2026

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    Arrives next day

    Greyhound USAFlixbus USALynx Central Florida Transport12h 3m • 2 changes

Departing Friday, November 13, 2026

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    Greyhound USAFlixbus USALynx Central Florida Transport9h 39m • 2 changes
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    Arrives next day

    Greyhound USAFlixbus USALynx Central Florida Transport12h 8m • 2 changes

Departing Saturday, November 14, 2026

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    Greyhound USAFlixbus USALynx Central Florida Transport9h 34m • 2 changes
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    Arrives next day

    Greyhound USAFlixbus USALynx Central Florida Transport12h 37m • 2 changes

Departing Sunday, November 15, 2026

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    Greyhound USAFlixbus USALynx Central Florida Transport9h 30m • 2 changes
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    Arrives next day

    Greyhound USAFlixbus USALynx Central Florida Transport12h 3m • 2 changes

Departing Monday, November 16, 2026

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    Greyhound USAFlixbus USALynx Central Florida Transport9h 39m • 2 changes
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    Arrives next day

    Greyhound USAFlixbus USALynx Central Florida Transport12h 3m • 2 changes

Departing Tuesday, November 17, 2026

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    Greyhound USAFlixbus USALynx Central Florida Transport9h 39m • 2 changes

Frequently asked questions

Want to know about travelling from Key West (Island) to Orlando? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Key West (Island) to Orlando.ExpandLaunch map view
  • Distance: 387 mi
  • Duration: 11h 31m

What companies run services between Key West (Island), FL, USA and Orlando, FL, USA?

You can take a bus from Key West Airport to Mccoy Rd & Central Ave via Miami Airport Station, Orlando, and Florida Mall in around 9h 54m.

Operators