Rome2Rio

Key West to Birmingham buses

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Trip Overview

The bus between Key West and Birmingham takes 24h 26m. The bus runs, on average, 6 times per week from Key West to Birmingham. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

24h 26m
Duration
981 mi
Distance
$201
Average price
6 times a week
Frequency

Key West to Birmingham bus times

Buses run 6 times a week between Key West and Birmingham. The service departs Key West at 7:39 AM in the morning, which arrives into Birmingham at 07:05:00. All services require a transfer at Big Pine Key - Auto Store / NAPA MM30 and take an average of 24h 26m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

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    Arrives next day

    Key West TransitGreyhound USAFlixbus USAGreyhound USA24h 26m • 3 changes

Departing Friday, November 13, 2026

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    Arrives next day

    Key West TransitGreyhound USAFlixbus USAGreyhound USA24h 26m • 3 changes

Departing Saturday, November 14, 2026

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    Arrives next day

    Key West TransitGreyhound USAFlixbus USAGreyhound USA24h 26m • 3 changes

Departing Sunday, November 15, 2026

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    Arrives next day

    Key West TransitGreyhound USAFlixbus USAGreyhound USA24h 26m • 3 changes

Departing Monday, November 16, 2026

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    Arrives next day

    Key West TransitGreyhound USAFlixbus USAGreyhound USA24h 26m • 3 changes

Departing Tuesday, November 17, 2026

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    Arrives next day

    Key West TransitGreyhound USAFlixbus USAGreyhound USA24h 26m • 3 changes

Frequently asked questions

Want to know about travelling from Key West to Birmingham? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Key West to Birmingham.ExpandLaunch map view
  • Distance: 980.8 mi
  • Duration: 24h 26m

What companies run services between Key West, FL, USA and Birmingham, AL, USA?

You can take a bus from N Roosevelt & 3rd Street to Birmingham Intermodal Facility via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, and Atlanta Bus Station in around 23h 27m.

Operators