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Key West to Brandon buses

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Trip Overview

The average bus between Key West and Brandon takes 15h 41m and the fastest bus takes 14h 49m. The bus service runs several times per day from Key West to Brandon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

15h 41m
Duration
462 mi
Distance
$95
Average price
Twice daily
Frequency

Key West to Brandon bus times

Buses run twice daily between Key West and Brandon. The earliest departure is at 7:39 AM in the morning, and the last departure from Key West is at 4:15 PM which arrives into Brandon at 7:11 AM. All services require a transfer at Big Pine Key - Auto Store / NAPA MM30 and take an average of 15h 41m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

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    Key West TransitGreyhound USAFlixbus USAHillsborough Area Regional Transit14h 49m • 3 changes
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    Arrives next day

    Key West TransitGreyhound USAFlixbus USAHillsborough Area Regional Transit14h 56m • 3 changes

Departing Thursday, November 12, 2026

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    Key West TransitGreyhound USAFlixbus USAHillsborough Area Regional Transit14h 49m • 3 changes
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    Arrives next day

    Key West TransitGreyhound USAFlixbus USAHillsborough Area Regional Transit14h 56m • 3 changes

Departing Friday, November 13, 2026

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    Key West TransitGreyhound USAFlixbus USAHillsborough Area Regional Transit14h 49m • 3 changes
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    Arrives next day

    Key West TransitGreyhound USAFlixbus USAHillsborough Area Regional Transit15h 44m • 3 changes

Departing Saturday, November 14, 2026

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    Key West TransitGreyhound USAFlixbus USAHillsborough Area Regional Transit15h 17m • 3 changes

Departing Sunday, November 15, 2026

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    Arrives next day

    Key West TransitGreyhound USAFlixbus USAHillsborough Area Regional Transit22h 32m • 3 changes
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    Arrives next day

    Key West TransitGreyhound USAFlixbus USAHillsborough Area Regional Transit14h 56m • 3 changes

Departing Monday, November 16, 2026

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    Key West TransitGreyhound USAFlixbus USAHillsborough Area Regional Transit14h 49m • 3 changes
  •  → 

    Arrives next day

    Key West TransitGreyhound USAFlixbus USAHillsborough Area Regional Transit14h 56m • 3 changes

Frequently asked questions

Want to know about travelling from Key West to Brandon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Key West to Brandon.ExpandLaunch map view
  • Distance: 462.1 mi
  • Duration: 15h 41m

What companies run services between Key West, FL, USA and Brandon, FL, USA?

You can take a bus from N Roosevelt & 3rd Street to Kings Av @ Oak Park Place via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, and Marion Transit Center in around 13h 47m.

Operators