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Key West to Cheeca Lodge & Spa, Islamorada buses

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Trip Overview

The average bus between Key West and Cheeca Lodge & Spa, Islamorada takes 3h 30m and the fastest bus takes 2h 54m. The bus service runs several times per day from Key West to Cheeca Lodge & Spa, Islamorada. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 30m
Duration
83 mi
Distance
$15
Average price
3 times a day
Frequency

Key West to Cheeca Lodge & Spa, Islamorada bus times

Buses run 3 times a day between Key West and Cheeca Lodge & Spa, Islamorada. The earliest departure is at 7:40 AM in the morning, and the last departure from Key West is at 4:16 PM which arrives into Cheeca Lodge & Spa, Islamorada at 7:10 PM. All services require a transfer at Big Pine Key - Auto Store / NAPA MM30 and take an average of 3h 30m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Key West TransitGreyhound USA4h 25m • 1 change
  •  → 

    Key West TransitGreyhound USA2h 54m • 1 change

Departing Thursday, November 12, 2026

  •  → 

    Key West TransitGreyhound USA4h 25m • 1 change
  •  → 

    Key West TransitGreyhound USA2h 54m • 1 change

Departing Friday, November 13, 2026

  •  → 

    Key West TransitGreyhound USA4h 25m • 1 change
  •  → 

    Key West TransitGreyhound USA3h 7m • 1 change
  •  → 

    Key West TransitGreyhound USA2h 54m • 1 change

Departing Saturday, November 14, 2026

  •  → 

    Key West TransitGreyhound USA4h 25m • 1 change
  •  → 

    Key West TransitGreyhound USA3h 7m • 1 change
  •  → 

    Key West TransitGreyhound USA2h 54m • 1 change

Departing Sunday, November 15, 2026

  •  → 

    Key West TransitGreyhound USA4h 25m • 1 change
  •  → 

    Key West TransitGreyhound USA3h 7m • 1 change
  •  → 

    Key West TransitGreyhound USA2h 54m • 1 change

Departing Monday, November 16, 2026

  •  → 

    Key West TransitGreyhound USA4h 25m • 1 change
  •  → 

    Key West TransitGreyhound USA3h 7m • 1 change
  •  → 

    Key West TransitGreyhound USA2h 54m • 1 change

Departing Tuesday, November 17, 2026

  •  → 

    Key West TransitGreyhound USA4h 25m • 1 change
  •  → 

    Key West TransitGreyhound USA3h 7m • 1 change
  •  → 

    Key West TransitGreyhound USA2h 54m • 1 change

Frequently asked questions

Want to know about travelling from Key West to Cheeca Lodge & Spa, Islamorada? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Key West to Cheeca Lodge & Spa, Islamorada.ExpandLaunch map view
  • Distance: 82.5 mi
  • Duration: 3h 30m

What companies run services between Key West, FL, USA and Cheeca Lodge & Spa, Islamorada, FL, USA?

You can take a bus from N Roosevelt & 4th Street to Cheeca Lodge & Spa, Islamorada via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, and Islamorada in around 3h 35m.

Operators