The average bus between Key West and Myrtle Beach takes 43h 50m and the fastest bus takes 43h 20m. The bus runs, on average, 2 times per week from Key West to Myrtle Beach. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice a week between Key West and Myrtle Beach. The service departs Key West at 4:15 PM in the afternoon, which arrives into Myrtle Beach at 11:35:00. All services require a transfer at Big Pine Key - Auto Store / NAPA MM30 and take an average of 43h 50m. The schedules shown below are for the next available departures.
Want to know about travelling from Key West to Myrtle Beach? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Key West to Myrtle Beach. However, there are services departing from N Roosevelt & 3rd Street station and arriving at Myrtle Beach Bus Station via Big Pine Key - Auto Store / NAPA MM30 station, Miami Airport Station and Fayetteville Bus Station. The journey, including transfers, takes approximately 43h 50m.
Key West to Myrtle Beach bus services, operated by Key West Transit, depart from N Roosevelt & 3rd Street station.
Key West to Myrtle Beach bus services, operated by Greyhound USA, arrive at Myrtle Beach Bus Station.
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The distance between Key West and Myrtle Beach is 1053.7 km. The road distance is 1342 km.
You can take a bus from N Roosevelt & 3rd Street to Myrtle Beach Bus Station via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, and Fayetteville Bus Station in around 26h 27m.