Rome2Rio

Kissimmee to Key West (Island) buses

Find Transport to Key West (Island)

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Trip Overview

The average bus between Kissimmee and Key West (Island) takes 28h 25m and the fastest bus takes 26h 56m. The bus runs, on average, 6 times per week from Kissimmee to Key West (Island). The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

28h 25m
Duration
380 mi
Distance
$82
Average price
6 times a week
Frequency

Kissimmee to Key West (Island) bus times

Buses run 6 times a week between Kissimmee and Key West (Island). The earliest departure is at 6:33 AM in the morning, and the last departure from Kissimmee is at 9:38 PM which arrives into Key West (Island) at 9:30 AM. All services require a transfer at Osceola Pkwy Walmart and take an average of 28h 25m. The schedules shown below are for the next available departures.

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    Lynx Central Florida TransportJet Set ExpressGreyhound USAGreyhound USA26h 56m • 3 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    Lynx Central Florida TransportJet Set ExpressGreyhound USAGreyhound USA26h 56m • 3 changes
  •  → 

    Arrives +2 days

    Lynx Central Florida TransportJet Set ExpressGreyhound USAGreyhound USA35h 52m • 3 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    Lynx Central Florida TransportJet Set ExpressGreyhound USAGreyhound USA26h 56m • 3 changes

Departing Tuesday, November 17, 2026

  •  → 

    Arrives next day

    Lynx Central Florida TransportJet Set ExpressGreyhound USAGreyhound USA26h 56m • 3 changes

Frequently asked questions

Want to know about travelling from Kissimmee to Key West (Island)? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Kissimmee to Key West (Island).ExpandLaunch map view
  • Distance: 380.1 mi
  • Duration: 28h 25m

What companies run services between Kissimmee, FL, USA and Key West (Island), FL, USA?

You can take a bus from E Vine St & Brack St to Key West Airport via Osceola Pkwy Walmart, Kissimmee -1471 East Osceola Parkway, Sheridan Tri-Rail Station, Sheridan Street Station, Miami, Airport Intermodal Station, and Miami Airport Station in around 11h 17m.

Operators