The average bus between Kissimmee and Key West (Island) takes 14h 50m and the fastest bus takes 10h 16m. The bus service runs several times per day from Kissimmee to Key West (Island). The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Kissimmee and Key West (Island). The earliest departure is at 4:48 AM at night, and the last departure from Kissimmee is at 10:13 PM which arrives into Key West (Island) at 12:30 PM. All services require a transfer at Osceola Pkwy Walmart and take an average of 14h 50m. The schedules shown below are for the next available departures.
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18h 39m • 2 changes
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17h 26m • 2 changes
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16h 15m • 2 changes
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14h 26m • 2 changes


10h 21m • 2 changes
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17h 15m • 2 changes
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14h 26m • 2 changes


10h 16m • 2 changes
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16h 46m • 2 changes
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14h 16m • 2 changes


10h 41m • 2 changes
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16h 46m • 2 changes
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15h 6m • 2 changes
Want to know about travelling from Kissimmee to Key West (Island)? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Kissimmee to Key West (Island). However, there are services departing from Kissimmee station and arriving at Key West (Island) station via Sheridan Tri-Rail Station station. The journey, including transfers, takes approximately 14h 50m.
Kissimmee to Key West (Island) bus services, operated by Lynx Central Florida Transport, depart from Kissimmee -1471 East Osceola Parkway station.
Kissimmee to Key West (Island) bus services, operated by Lynx Central Florida Transport, arrive at Key West Airport station.
The distance between Kissimmee and Key West (Island) is 418.7 km. The road distance is 612 km.
You can take a bus from E Vine St & Brack St to Key West Airport via Osceola Pkwy Walmart, Kissimmee -1471 East Osceola Parkway, Sheridan Tri-Rail Station, Sheridan Street Station, Miami, Airport Intermodal Station, and Miami Airport Station in around 11h 16m.