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The bus between La Crosse and Buffalo takes 32h 10m. The bus runs, on average, 6 times per week from La Crosse to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 6 times a week between La Crosse and Buffalo. The service departs La Crosse at 2:30 PM in the afternoon, which arrives into Buffalo at 22:40:00. All services require a transfer at Milwaukee and take an average of 32h 10m. The schedules shown below are for the next available departures.
Want to know about travelling from La Crosse to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from La Crosse to Buffalo. However, there are services departing from La Crosse station and arriving at Buffalo station via Milwaukee station, Chicago Bus Station and Cleveland station. The journey, including transfers, takes approximately 32h 10m.
La Crosse to Buffalo bus services, operated by Jefferson Lines, depart from La Crosse station.
La Crosse to Buffalo bus services, operated by Barons Bus, arrive at Buffalo station.
Book your La Crosse to Buffalo bus tickets online with Omio.
The distance between La Crosse and Buffalo is 1003.8 km. The road distance is 1307 km.
You can take a bus from La Crosse to Buffalo via Milwaukee, Milwaukee Intermodal Station, Chicago, and Cleveland in around 18h 30m.
