The bus between La Crosse and Buffalo takes 32h 10m. The bus runs, on average, 6 times per week from La Crosse to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 6 times a week between La Crosse and Buffalo. The earliest departure is at 2:30 PM in the afternoon, and the last departure from La Crosse is at 2:30 PM which arrives into Buffalo at 10:40 PM. All services require a transfer at Milwaukee and take an average of 32h 10m. The schedules shown below are for the next available departures.
Want to know about travelling from La Crosse to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from La Crosse to Buffalo. However, there are services departing from La Crosse station and arriving at Buffalo station via Milwaukee. The journey, including transfers, takes approximately 32h 10m.
La Crosse to Buffalo bus services, operated by Jefferson Lines, depart from La Crosse station.
La Crosse to Buffalo bus services, operated by Jefferson Lines, arrive at Buffalo, NY station.
Book your La Crosse to Buffalo bus tickets online with Jefferson Lines, Greyhound USA and Barons Bus.
The distance between La Crosse and Buffalo is 1,003.8 km. The road distance is 1,340 km.
You can take a bus from La Crosse to Buffalo, NY via Milwaukee, Milwaukee Intermodal Station, Chicago, and Cleveland, OH in around 18h 30m.
