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La Crosse to Champaign buses

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Trip Overview

The average bus between La Crosse and Champaign takes 15h 22m and the fastest bus takes 13h 30m. The bus runs, on average, 6 times per week from La Crosse to Champaign. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

15h 22m
Duration
427 mi
Distance
$110
Average price
6 times a week
Frequency

La Crosse to Champaign bus times

Buses run 6 times a week between La Crosse and Champaign. The service departs La Crosse at 2:30 PM in the afternoon, which arrives into Champaign at 03:00:00. All services require a transfer at Milwaukee and take an average of 15h 22m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

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    Arrives next day

    Jefferson LinesGreyhound USAFlixbus USA13h 30m • 2 changes

Departing Thursday, November 12, 2026

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    Arrives next day

    Jefferson LinesGreyhound USAFlixbus USA13h 30m • 2 changes

Departing Friday, November 13, 2026

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    Arrives next day

    Jefferson LinesGreyhound USAFlixbus USA13h 30m • 2 changes

Departing Saturday, November 14, 2026

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    Arrives next day

    Jefferson LinesGreyhound USAFlixbus USA13h 30m • 2 changes

Departing Sunday, November 15, 2026

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    Arrives next day

    Jefferson LinesGreyhound USAFlixbus USA13h 30m • 2 changes

Departing Monday, November 16, 2026

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    Arrives next day

    Jefferson LinesFlixbus USAPeoria Charter Coach Company24h 45m • 2 changes

Frequently asked questions

Want to know about travelling from La Crosse to Champaign? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from La Crosse to Champaign.ExpandLaunch map view
  • Distance: 426.9 mi
  • Duration: 15h 22m

What companies run services between La Crosse, WI, USA and Champaign, IL, USA?

You can take a bus from La Crosse to Illinois Terminal via Milwaukee, Milwaukee Intermodal Station, Chicago Bus Station, and Downtown Chicago in around 10h 15m.

Operators