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La Crosse to Iowa City buses

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Trip Overview

The bus between La Crosse and Iowa City takes 22h 35m. The bus runs, on average, 6 times per week from La Crosse to Iowa City. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

22h 35m
Duration
515 mi
Distance
$151
Average price
6 times a week
Frequency

La Crosse to Iowa City bus times

Buses run 6 times a week between La Crosse and Iowa City. The service departs La Crosse at 2:30 PM in the afternoon, which arrives into Iowa City at 12:05:00. All services require a transfer at Madison and take an average of 22h 35m. The schedules shown below are for the next available departures.

Departing Saturday, November 7, 2026

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    Arrives next day

    Jefferson LinesRockland CoachesGreyhound USA22h 35m • 2 changes

Departing Sunday, November 8, 2026

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    Arrives next day

    Jefferson LinesRockland CoachesGreyhound USA22h 35m • 2 changes

Departing Monday, November 9, 2026

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    Arrives next day

    Jefferson LinesRockland CoachesGreyhound USA22h 35m • 2 changes

Departing Tuesday, November 10, 2026

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    Arrives next day

    Jefferson LinesRockland CoachesGreyhound USA22h 35m • 2 changes

Departing Wednesday, November 11, 2026

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    Arrives next day

    Jefferson LinesRockland CoachesGreyhound USA22h 35m • 2 changes

Departing Thursday, November 12, 2026

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    Arrives next day

    Jefferson LinesRockland CoachesGreyhound USA22h 35m • 2 changes

Frequently asked questions

Want to know about travelling from La Crosse to Iowa City? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from La Crosse to Iowa City.ExpandLaunch map view
  • Distance: 515.5 mi
  • Duration: 22h 35m

What companies run services between La Crosse, WI, USA and Iowa City, IA, USA?

You can take a bus from La Crosse to Iowa City via Madison, 250 N. Lake St - Madison UW Campus, W Jackson Blvd, after S Clinton St, and Chicago Bus Station in around 13h 58m.

Operators