Rome2Rio

La Crosse to Iowa City buses

Find Transport to Iowa City

View schedule

Trip Overview

The bus between La Crosse and Iowa City takes 19h 50m. The bus runs, on average, 6 times per week from La Crosse to Iowa City. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

19h 50m
Duration
506 mi
Distance
$132
Average price
6 times a week
Frequency

La Crosse to Iowa City bus times

Buses run 6 times a week between La Crosse and Iowa City. The service departs La Crosse at 12:50 PM in the afternoon, which arrives into Iowa City at 07:40:00. All services require a transfer at Saint Paul Union Depot and take an average of 19h 50m. The schedules shown below are for the next available departures.

Departing Wednesday, November 4, 2026

  •  → 

    Arrives next day

    Jefferson LinesGreyhound USAGreyhound USA19h 50m • 2 changes

Departing Thursday, November 5, 2026

  •  → 

    Arrives next day

    Jefferson LinesGreyhound USAGreyhound USA19h 50m • 2 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives next day

    Jefferson LinesGreyhound USAGreyhound USA19h 50m • 2 changes

Departing Saturday, November 7, 2026

  •  → 

    Arrives next day

    Jefferson LinesGreyhound USAGreyhound USA19h 50m • 2 changes

Departing Sunday, November 8, 2026

  •  → 

    Arrives next day

    Jefferson LinesGreyhound USAGreyhound USA19h 50m • 2 changes

Departing Monday, November 9, 2026

  •  → 

    Arrives next day

    Jefferson LinesGreyhound USAGreyhound USA19h 50m • 2 changes

Frequently asked questions

Want to know about travelling from La Crosse to Iowa City? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from La Crosse to Iowa City.ExpandLaunch map view
  • Distance: 506.5 mi
  • Duration: 19h 50m

What companies run services between La Crosse, WI, USA and Iowa City, IA, USA?

You can take a bus from La Crosse to Iowa City via Saint Paul Union Depot and Des Moines in around 12h.

Operators