Rome2Rio

La Crosse to O'Hare buses

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Trip Overview

The bus between La Crosse and O'Hare takes 18h 35m. The bus runs, on average, 6 times per week from La Crosse to O'Hare. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

18h 35m
Duration
281 mi
Distance
$82
Average price
6 times a week
Frequency

La Crosse to O'Hare bus times

Buses run 6 times a week between La Crosse and O'Hare. The service departs La Crosse at 2:30 PM in the afternoon, which arrives into O'Hare at 08:05:00. All services require a transfer at Milwaukee and take an average of 18h 35m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

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    Arrives next day

    Jefferson LinesGreyhound USA18h 35m • 1 change

Departing Wednesday, November 11, 2026

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    Arrives next day

    Jefferson LinesGreyhound USA18h 35m • 1 change

Departing Thursday, November 12, 2026

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    Arrives next day

    Jefferson LinesGreyhound USA18h 35m • 1 change

Departing Friday, November 13, 2026

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    Arrives next day

    Jefferson LinesGreyhound USA18h 35m • 1 change

Departing Saturday, November 14, 2026

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    Arrives next day

    Jefferson LinesGreyhound USA18h 35m • 1 change

Departing Sunday, November 15, 2026

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    Arrives next day

    Jefferson LinesGreyhound USA18h 35m • 1 change

Frequently asked questions

Want to know about travelling from La Crosse to O'Hare? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from La Crosse to O'Hare.ExpandLaunch map view
  • Distance: 281 mi
  • Duration: 18h 35m

What companies run services between La Crosse, WI, USA and O'Hare, IL, USA?

You can take a bus from La Crosse to Chicago via Milwaukee and Milwaukee Intermodal Station in around 6h 10m.

Operators