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La Crosse to Rochester buses

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Trip Overview

The average bus between La Crosse and Rochester takes 34h 54m and the fastest bus takes 34h. The bus runs, on average, 5 times per week from La Crosse to Rochester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

34h 54m
Duration
906 mi
Distance
$200
Average price
5 times a week
Frequency

La Crosse to Rochester bus times

Buses run 5 times a week between La Crosse and Rochester. The service departs La Crosse at 2:30 PM in the afternoon, which arrives into Rochester at 00:30:00. All services require a transfer at Milwaukee and take an average of 34h 54m. The schedules shown below are for the next available departures.

Departing Saturday, November 7, 2026

  •  → 

    Arrives +2 days

    Jefferson LinesGreyhound USABarons BusBarons BusFlixbus USA34h • 4 changes

Departing Sunday, November 8, 2026

  •  → 

    Arrives +2 days

    Jefferson LinesGreyhound USABarons BusBarons BusFlixbus USA34h • 4 changes

Departing Monday, November 9, 2026

  •  → 

    Arrives +2 days

    Jefferson LinesGreyhound USABarons BusBarons BusFlixbus USA38h 30m • 4 changes

Departing Tuesday, November 10, 2026

  •  → 

    Arrives +2 days

    Jefferson LinesGreyhound USABarons BusBarons BusFlixbus USA34h • 4 changes

Departing Wednesday, November 11, 2026

  •  → 

    Arrives +2 days

    Jefferson LinesGreyhound USABarons BusBarons BusFlixbus USA34h • 4 changes

Frequently asked questions

Want to know about travelling from La Crosse to Rochester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from La Crosse to Rochester.ExpandLaunch map view
  • Distance: 906.4 mi
  • Duration: 34h 54m

What companies run services between La Crosse, WI, USA and Rochester, NY, USA?

You can take a bus from La Crosse to Rochester Bus Stop via Milwaukee, Milwaukee Intermodal Station, Chicago, Cleveland, and Buffalo in around 20h 26m.

Operators